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Optogenetic and chemogenetic manipulation of seizure threshold in mice
Here, we present a protocol using optogenetics or chemogenetics to assess the neuronal circuits contributing to seizure initiation. Both approaches allow for targeted control of neuronal populations in vivo and can be combined with experimental manipulations to acutely induce seizures in rodent mode...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846020/ https://www.ncbi.nlm.nih.gov/pubmed/36640370 http://dx.doi.org/10.1016/j.xpro.2022.102019 |