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Safety of 27 flavouring compounds providing a milky‐vanilla flavour and belonging to different chemical groups for use as feed additives in all animal species (FEFANA asbl)

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety of 27 compounds to provide a milky‐vanilla flavour belonging to different chemical groups, when used as sensory additives in feed for all animal species. Fifteen of the 27 compounds were te...

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Autores principales: Bampidis, Vasileios, Azimonti, Giovanna, Bastos, Maria de Lourdes, Christensen, Henrik, Dusemund, Birgit, Fašmon Durjava, Mojca, Kouba, Maryline, López‐Alonso, Marta, López Puente, Secundino, Marcon, Francesca, Mayo, Baltasar, Pechová, Alena, Petkova, Mariana, Ramos, Fernando, Sanz, Yolanda, Villa, Roberto Edoardo, Woutersen, Ruud, Brantom, Paul, Chesson, Andrew, Dierick, Noël, Martelli, Giovanna, Westendorf, Johannes, Anguita, Montserrat, Ortuño Casanova, Jordi, Manini, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846309/
https://www.ncbi.nlm.nih.gov/pubmed/36698489
http://dx.doi.org/10.2903/j.efsa.2023.7713
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author Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Fašmon Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Brantom, Paul
Chesson, Andrew
Dierick, Noël
Martelli, Giovanna
Westendorf, Johannes
Anguita, Montserrat
Ortuño Casanova, Jordi
Manini, Paola
author_facet Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Fašmon Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Brantom, Paul
Chesson, Andrew
Dierick, Noël
Martelli, Giovanna
Westendorf, Johannes
Anguita, Montserrat
Ortuño Casanova, Jordi
Manini, Paola
collection PubMed
description Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety of 27 compounds to provide a milky‐vanilla flavour belonging to different chemical groups, when used as sensory additives in feed for all animal species. Fifteen of the 27 compounds were tested in tolerance studies in chickens for fattening, piglets and cattle for fattening. No adverse effects were observed in the tolerance studies at 10‐fold the intended level. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the 15 tested compounds were safe for these species at the proposed use level and conclusions were extrapolated to all animal species. For the remaining 12 compounds, read‐across from structurally similar compounds tested in tolerance trials and belonging to the same chemical group was applied. The FEEDAP Panel concluded that these 12 compounds were safe for all animal species at the proposed use level. No safety concern would arise for the consumer from the use of the 27 compounds up to the highest levels considered safe for target animals. No new data were submitted on the safety for the user that would allow the FEEDAP Panel to change its previous conclusion for 5‐methylhept‐2‐en‐4‐one [07.139], 5‐methylfurfural [13.001] and 4‐phenylbut‐3‐en‐2‐one [07.024]. The concentrations considered safe for the target species are unlikely to have detrimental effects on the environment for all the compounds.
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spelling pubmed-98463092023-01-24 Safety of 27 flavouring compounds providing a milky‐vanilla flavour and belonging to different chemical groups for use as feed additives in all animal species (FEFANA asbl) Bampidis, Vasileios Azimonti, Giovanna Bastos, Maria de Lourdes Christensen, Henrik Dusemund, Birgit Fašmon Durjava, Mojca Kouba, Maryline López‐Alonso, Marta López Puente, Secundino Marcon, Francesca Mayo, Baltasar Pechová, Alena Petkova, Mariana Ramos, Fernando Sanz, Yolanda Villa, Roberto Edoardo Woutersen, Ruud Brantom, Paul Chesson, Andrew Dierick, Noël Martelli, Giovanna Westendorf, Johannes Anguita, Montserrat Ortuño Casanova, Jordi Manini, Paola EFSA J Scientific Opinion Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety of 27 compounds to provide a milky‐vanilla flavour belonging to different chemical groups, when used as sensory additives in feed for all animal species. Fifteen of the 27 compounds were tested in tolerance studies in chickens for fattening, piglets and cattle for fattening. No adverse effects were observed in the tolerance studies at 10‐fold the intended level. The Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) concluded that the 15 tested compounds were safe for these species at the proposed use level and conclusions were extrapolated to all animal species. For the remaining 12 compounds, read‐across from structurally similar compounds tested in tolerance trials and belonging to the same chemical group was applied. The FEEDAP Panel concluded that these 12 compounds were safe for all animal species at the proposed use level. No safety concern would arise for the consumer from the use of the 27 compounds up to the highest levels considered safe for target animals. No new data were submitted on the safety for the user that would allow the FEEDAP Panel to change its previous conclusion for 5‐methylhept‐2‐en‐4‐one [07.139], 5‐methylfurfural [13.001] and 4‐phenylbut‐3‐en‐2‐one [07.024]. The concentrations considered safe for the target species are unlikely to have detrimental effects on the environment for all the compounds. John Wiley and Sons Inc. 2023-01-18 /pmc/articles/PMC9846309/ /pubmed/36698489 http://dx.doi.org/10.2903/j.efsa.2023.7713 Text en © 2023 Wiley‐VCH Verlag GmbH & Co. KgaA on behalf of the European Food Safety Authority. https://creativecommons.org/licenses/by-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ (https://creativecommons.org/licenses/by-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Scientific Opinion
Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Dusemund, Birgit
Fašmon Durjava, Mojca
Kouba, Maryline
López‐Alonso, Marta
López Puente, Secundino
Marcon, Francesca
Mayo, Baltasar
Pechová, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Brantom, Paul
Chesson, Andrew
Dierick, Noël
Martelli, Giovanna
Westendorf, Johannes
Anguita, Montserrat
Ortuño Casanova, Jordi
Manini, Paola
Safety of 27 flavouring compounds providing a milky‐vanilla flavour and belonging to different chemical groups for use as feed additives in all animal species (FEFANA asbl)
title Safety of 27 flavouring compounds providing a milky‐vanilla flavour and belonging to different chemical groups for use as feed additives in all animal species (FEFANA asbl)
title_full Safety of 27 flavouring compounds providing a milky‐vanilla flavour and belonging to different chemical groups for use as feed additives in all animal species (FEFANA asbl)
title_fullStr Safety of 27 flavouring compounds providing a milky‐vanilla flavour and belonging to different chemical groups for use as feed additives in all animal species (FEFANA asbl)
title_full_unstemmed Safety of 27 flavouring compounds providing a milky‐vanilla flavour and belonging to different chemical groups for use as feed additives in all animal species (FEFANA asbl)
title_short Safety of 27 flavouring compounds providing a milky‐vanilla flavour and belonging to different chemical groups for use as feed additives in all animal species (FEFANA asbl)
title_sort safety of 27 flavouring compounds providing a milky‐vanilla flavour and belonging to different chemical groups for use as feed additives in all animal species (fefana asbl)
topic Scientific Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846309/
https://www.ncbi.nlm.nih.gov/pubmed/36698489
http://dx.doi.org/10.2903/j.efsa.2023.7713
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