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Leucine mediates cognitive dysfunction in early life stress-induced mental disorders by activating autophagy

OBJECTIVES: To explore the relationship between leucine in cerebrospinal fluid (CSF) and cognitive dysfunction in rats with early life stress (ELS) induced mental illness, and pathophysiological mechanism involved. METHODS: The maternal separation (MS), an animal paradigm used widely as a preclinica...

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Detalles Bibliográficos
Autores principales:	Wang, Xiaotian, Wang, Xue, Xie, Fang, Sun, Zhaowei, Guo, Bomin, Li, Feng, Wang, Shida, Wang, Ying, Tian, Yingrui, Zhao, Yun, Qian, Lingjia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Cellular Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846360/ https://www.ncbi.nlm.nih.gov/pubmed/36687518 http://dx.doi.org/10.3389/fncel.2022.1060712

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