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Histone H3 core domain in chromatin with different DNA linker lengths studied by (1)H-Detected solid-state NMR spectroscopy

Chromatin, a dynamic protein-DNA complex that regulates eukaryotic genome accessibility and essential functions, is composed of nucleosomes connected by linker DNA with each nucleosome consisting of DNA wrapped around an octamer of histones H2A, H2B, H3 and H4. Magic angle spinning solid-state nucle...

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Detalles Bibliográficos
Autores principales: Smrt, Sean T., Gonzalez Salguero, Nicole, Thomas, Justin K., Zandian, Mohamad, Poirier, Michael G., Jaroniec, Christopher P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846530/
https://www.ncbi.nlm.nih.gov/pubmed/36660422
http://dx.doi.org/10.3389/fmolb.2022.1106588