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Amelioration of cognitive impairment using epigallocatechin-3-gallate in ovariectomized mice fed a high-fat diet involves remodeling with Prevotella and Bifidobacteriales

Background: Estrogen deficiency and a high-fat diet (HFD) are both risk factors for Alzheimer’s disease (AD). HFD can accelerate cognitive impairment in estrogen-deficient patients, but there is currently no effective treatment. Epigallocatechin-3-galate (EGCG) is widely studied for its anti-inflamm...

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Detalles Bibliográficos
Autores principales: Qu, Yang, Wu, Yan, Cheng, Wei, Wang, Dongyang, Zeng, Lu, Wang, Yanru, Li, Tingting, Zhang, Liye, Yang, Jinan, Sun, Liyang, Ai, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846573/
https://www.ncbi.nlm.nih.gov/pubmed/36686657
http://dx.doi.org/10.3389/fphar.2022.1079313