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IgE-dependent human basophil responses are inversely associated with the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA)
Basophils crucially contribute to allergies and other Th2-driven diseases by rapidly releasing inflammatory and immunomodulatory mediators following high-affinity IgE-receptor crosslinking. Although these basophil-mediated responses depend on sensitization with antigen-specific IgE, this does not ne...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846818/ https://www.ncbi.nlm.nih.gov/pubmed/36685580 http://dx.doi.org/10.3389/fimmu.2022.1052290 |