Cargando…

IgE-dependent human basophil responses are inversely associated with the sarcoplasmic reticulum Ca(2+)-ATPase (SERCA)

Basophils crucially contribute to allergies and other Th2-driven diseases by rapidly releasing inflammatory and immunomodulatory mediators following high-affinity IgE-receptor crosslinking. Although these basophil-mediated responses depend on sensitization with antigen-specific IgE, this does not ne...

Descripción completa

Detalles Bibliográficos
Autores principales: Selnø, Anette T. Hansen, Sumbayev, Vadim V., Gibbs, Bernhard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846818/
https://www.ncbi.nlm.nih.gov/pubmed/36685580
http://dx.doi.org/10.3389/fimmu.2022.1052290