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Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio

BACKGROUND AND AIMS: Due to increased rate of open‐heart surgeries in children, postsurgical mortality and morbidities have increasingly gained attention. Neurological complications are some of the most important postsurgical events. However, the number of studies regarding postsurgical neurological...

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Autores principales: Abdshah, Alireza, Mirzaaghayan, Mohammadreza, Heidari, Morteza, Memarian, Sara, Amanollahi, Mobina, Nazeri, Azadeh, Gharib, Behdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846836/
https://www.ncbi.nlm.nih.gov/pubmed/36698707
http://dx.doi.org/10.1002/hsr2.1077
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author Abdshah, Alireza
Mirzaaghayan, Mohammadreza
Heidari, Morteza
Memarian, Sara
Amanollahi, Mobina
Nazeri, Azadeh
Gharib, Behdad
author_facet Abdshah, Alireza
Mirzaaghayan, Mohammadreza
Heidari, Morteza
Memarian, Sara
Amanollahi, Mobina
Nazeri, Azadeh
Gharib, Behdad
author_sort Abdshah, Alireza
collection PubMed
description BACKGROUND AND AIMS: Due to increased rate of open‐heart surgeries in children, postsurgical mortality and morbidities have increasingly gained attention. Neurological complications are some of the most important postsurgical events. However, the number of studies regarding postsurgical neurological complications seems to be inadequate. We aimed to study the incidence of neurological complications following cardiac surgery in the pediatric cardiac intensive care unit (ICU) of the children's medical center. METHODS: This cross‐sectional study was conducted from March to September 2019. We included all of the children who underwent cardiac surgery and were admitted to ICU at CMC. We collected their demographic data, lab test results (white blood cell count, absolute neutrophile and lymphocyte counts) and calculated their Risk Adjustment for Congenital Heart Surgery (RACHS) score. We then documented neurological adverse events and investigated the associations between those events and the patients' data. RESULTS: Of the 267 studied patients, 14 developed neurological complications (5.2%); seven developed chorea (2.6%), four developed seizures (1.5%), and two developed both seizure and chorea (0.7%). One case developed subarachnoid hemorrhage (SAH). We observed that age (p = 0.000), weight (p = 0.000), and RACHS score (p = 0.006) were associated with the development of neurological complications. Additionally, we observed that “neutrophil to lymphocyte ratio” was not associated with the risk of postsurgical neurological complications. CONCLUSION: Younger age, lower weight, and higher RACHS score were associated with neurological complications after operations. Given the importance of postsurgical neurological complications, further investigations should be carried out to cover this issue and discover preventive strategies for such morbidities.
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spelling pubmed-98468362023-01-24 Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio Abdshah, Alireza Mirzaaghayan, Mohammadreza Heidari, Morteza Memarian, Sara Amanollahi, Mobina Nazeri, Azadeh Gharib, Behdad Health Sci Rep Original Research BACKGROUND AND AIMS: Due to increased rate of open‐heart surgeries in children, postsurgical mortality and morbidities have increasingly gained attention. Neurological complications are some of the most important postsurgical events. However, the number of studies regarding postsurgical neurological complications seems to be inadequate. We aimed to study the incidence of neurological complications following cardiac surgery in the pediatric cardiac intensive care unit (ICU) of the children's medical center. METHODS: This cross‐sectional study was conducted from March to September 2019. We included all of the children who underwent cardiac surgery and were admitted to ICU at CMC. We collected their demographic data, lab test results (white blood cell count, absolute neutrophile and lymphocyte counts) and calculated their Risk Adjustment for Congenital Heart Surgery (RACHS) score. We then documented neurological adverse events and investigated the associations between those events and the patients' data. RESULTS: Of the 267 studied patients, 14 developed neurological complications (5.2%); seven developed chorea (2.6%), four developed seizures (1.5%), and two developed both seizure and chorea (0.7%). One case developed subarachnoid hemorrhage (SAH). We observed that age (p = 0.000), weight (p = 0.000), and RACHS score (p = 0.006) were associated with the development of neurological complications. Additionally, we observed that “neutrophil to lymphocyte ratio” was not associated with the risk of postsurgical neurological complications. CONCLUSION: Younger age, lower weight, and higher RACHS score were associated with neurological complications after operations. Given the importance of postsurgical neurological complications, further investigations should be carried out to cover this issue and discover preventive strategies for such morbidities. John Wiley and Sons Inc. 2023-01-18 /pmc/articles/PMC9846836/ /pubmed/36698707 http://dx.doi.org/10.1002/hsr2.1077 Text en © 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Abdshah, Alireza
Mirzaaghayan, Mohammadreza
Heidari, Morteza
Memarian, Sara
Amanollahi, Mobina
Nazeri, Azadeh
Gharib, Behdad
Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio
title Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio
title_full Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio
title_fullStr Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio
title_full_unstemmed Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio
title_short Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio
title_sort incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846836/
https://www.ncbi.nlm.nih.gov/pubmed/36698707
http://dx.doi.org/10.1002/hsr2.1077
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