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Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio
BACKGROUND AND AIMS: Due to increased rate of open‐heart surgeries in children, postsurgical mortality and morbidities have increasingly gained attention. Neurological complications are some of the most important postsurgical events. However, the number of studies regarding postsurgical neurological...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846836/ https://www.ncbi.nlm.nih.gov/pubmed/36698707 http://dx.doi.org/10.1002/hsr2.1077 |
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author | Abdshah, Alireza Mirzaaghayan, Mohammadreza Heidari, Morteza Memarian, Sara Amanollahi, Mobina Nazeri, Azadeh Gharib, Behdad |
author_facet | Abdshah, Alireza Mirzaaghayan, Mohammadreza Heidari, Morteza Memarian, Sara Amanollahi, Mobina Nazeri, Azadeh Gharib, Behdad |
author_sort | Abdshah, Alireza |
collection | PubMed |
description | BACKGROUND AND AIMS: Due to increased rate of open‐heart surgeries in children, postsurgical mortality and morbidities have increasingly gained attention. Neurological complications are some of the most important postsurgical events. However, the number of studies regarding postsurgical neurological complications seems to be inadequate. We aimed to study the incidence of neurological complications following cardiac surgery in the pediatric cardiac intensive care unit (ICU) of the children's medical center. METHODS: This cross‐sectional study was conducted from March to September 2019. We included all of the children who underwent cardiac surgery and were admitted to ICU at CMC. We collected their demographic data, lab test results (white blood cell count, absolute neutrophile and lymphocyte counts) and calculated their Risk Adjustment for Congenital Heart Surgery (RACHS) score. We then documented neurological adverse events and investigated the associations between those events and the patients' data. RESULTS: Of the 267 studied patients, 14 developed neurological complications (5.2%); seven developed chorea (2.6%), four developed seizures (1.5%), and two developed both seizure and chorea (0.7%). One case developed subarachnoid hemorrhage (SAH). We observed that age (p = 0.000), weight (p = 0.000), and RACHS score (p = 0.006) were associated with the development of neurological complications. Additionally, we observed that “neutrophil to lymphocyte ratio” was not associated with the risk of postsurgical neurological complications. CONCLUSION: Younger age, lower weight, and higher RACHS score were associated with neurological complications after operations. Given the importance of postsurgical neurological complications, further investigations should be carried out to cover this issue and discover preventive strategies for such morbidities. |
format | Online Article Text |
id | pubmed-9846836 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98468362023-01-24 Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio Abdshah, Alireza Mirzaaghayan, Mohammadreza Heidari, Morteza Memarian, Sara Amanollahi, Mobina Nazeri, Azadeh Gharib, Behdad Health Sci Rep Original Research BACKGROUND AND AIMS: Due to increased rate of open‐heart surgeries in children, postsurgical mortality and morbidities have increasingly gained attention. Neurological complications are some of the most important postsurgical events. However, the number of studies regarding postsurgical neurological complications seems to be inadequate. We aimed to study the incidence of neurological complications following cardiac surgery in the pediatric cardiac intensive care unit (ICU) of the children's medical center. METHODS: This cross‐sectional study was conducted from March to September 2019. We included all of the children who underwent cardiac surgery and were admitted to ICU at CMC. We collected their demographic data, lab test results (white blood cell count, absolute neutrophile and lymphocyte counts) and calculated their Risk Adjustment for Congenital Heart Surgery (RACHS) score. We then documented neurological adverse events and investigated the associations between those events and the patients' data. RESULTS: Of the 267 studied patients, 14 developed neurological complications (5.2%); seven developed chorea (2.6%), four developed seizures (1.5%), and two developed both seizure and chorea (0.7%). One case developed subarachnoid hemorrhage (SAH). We observed that age (p = 0.000), weight (p = 0.000), and RACHS score (p = 0.006) were associated with the development of neurological complications. Additionally, we observed that “neutrophil to lymphocyte ratio” was not associated with the risk of postsurgical neurological complications. CONCLUSION: Younger age, lower weight, and higher RACHS score were associated with neurological complications after operations. Given the importance of postsurgical neurological complications, further investigations should be carried out to cover this issue and discover preventive strategies for such morbidities. John Wiley and Sons Inc. 2023-01-18 /pmc/articles/PMC9846836/ /pubmed/36698707 http://dx.doi.org/10.1002/hsr2.1077 Text en © 2023 The Authors. Health Science Reports published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Abdshah, Alireza Mirzaaghayan, Mohammadreza Heidari, Morteza Memarian, Sara Amanollahi, Mobina Nazeri, Azadeh Gharib, Behdad Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio |
title | Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio |
title_full | Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio |
title_fullStr | Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio |
title_full_unstemmed | Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio |
title_short | Incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio |
title_sort | incidence of neurological complications following pediatric heart surgery and its association with neutrophil‐to‐lymphocyte ratio |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9846836/ https://www.ncbi.nlm.nih.gov/pubmed/36698707 http://dx.doi.org/10.1002/hsr2.1077 |
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