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Enhancement of radiation therapy by indoleamine 2,3 dioxygenase 1 inhibition through multimodal mechanisms

BACKGROUND: Indoleamine 2,3-dioxygenase 1 (IDO1) is an enzyme that converts tryptophan to kynurenine. IDO1 expression is found not only in tumor cells but also in immune cells and is associated with tumor proliferation and immune responses. IDO1 inhibitors and radiation may cooperatively suppress tu...

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Detalles Bibliográficos
Autores principales:	Nozawa, Hiroaki, Taira, Tetsuro, Sonoda, Hirofumi, Sasaki, Kazuhito, Murono, Koji, Emoto, Shigenobu, Yokoyama, Yuichiro, Nagai, Yuzo, Abe, Shinya, Ishihara, Soichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847047/ https://www.ncbi.nlm.nih.gov/pubmed/36653774 http://dx.doi.org/10.1186/s12885-023-10539-5

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