Cargando…

Inactivation of ZSCAN18 by promoter hypermethylation drives the proliferation via attenuating TP53INP2-mediated autophagy in gastric cancer cells

BACKGROUND: Zinc finger and scan domain containing 18 (ZSCAN18) belongs to the zinc finger transcription factor superfamily, which consists of hundreds of members that play critical roles in all steps of tumorigenesis. METHODS: This study aims to investigate the roles of ZSCAN18 in gastric cancer (G...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Bin, Ren, Baoqing, Ma, Gang, Cai, Fenglin, Wang, Pengliang, Zeng, Yi, Liu, Yong, Zhang, Li, Yang, Yang, Liang, Han, Zhang, Rupeng, Deng, Jingyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847086/ https://www.ncbi.nlm.nih.gov/pubmed/36650573 http://dx.doi.org/10.1186/s13148-023-01425-9

Ejemplares similares

DOR/Tp53inp2 and Tp53inp1 Constitute a Metazoan Gene Family Encoding Dual Regulators of Autophagy and Transcription
por: Sancho, Ana, et al.
Publicado: (2012)

TP53INP2 Promotes Bovine Adipocytes Differentiation Through Autophagy Activation
por: Zhang, Weiyi, et al.
Publicado: (2019)

Correction: DOR/Tp53inp2 and Tp53inp1 Constitute a Metazoan Gene Family Encoding Dual Regulators of Autophagy and Transcription
por: Sancho, Ana, et al.
Publicado: (2012)

Correction: DOR/Tp53inp2 and Tp53inp1 Constitute a Metazoan Gene Family Encoding Dual Regulators of Autophagy and Transcription
por: Sancho, Ana, et al.
Publicado: (2012)

Cytoplasmic Expression of TP53INP2 Modulated by Demethylase FTO and Mutant NPM1 Promotes Autophagy in Leukemia Cells
por: Huang, Junpeng, et al.
Publicado: (2023)

Redox-sensitive TP53INP1 SUMOylation as an oxidative stress sensor to activate TP53
por: Bonacci, Thomas, et al.
Publicado: (2014)

Integrative Analysis of TP53INP2 in Head and Neck Squamous Cell Carcinoma
por: Cao, Ruoyan, et al.
Publicado: (2021)

MicroRNA-106a regulates autophagy-related cell death and EMT by targeting TP53INP1 in lung cancer with bone metastasis
por: Han, Lei, et al.
Publicado: (2021)

SMYD3 drives the proliferation in gastric cancer cells via reducing EMP1 expression in an H4K20me3-dependent manner
por: Zeng, Yi, et al.
Publicado: (2023)

TP53INP2 Contributes to TGF-β2-Induced Autophagy during the Epithelial–Mesenchymal Transition in Posterior Capsular Opacification Development
por: Cui, Yilei, et al.
Publicado: (2022)

miR-106b regulates the proliferation and differentiation of neural stem/progenitor cells through Tp53inp1-Tp53-Cdkn1a axis
por: Xia, Xiaohuan, et al.
Publicado: (2019)

Paclitaxel Induce Apoptosis of Giant Cells Tumor of Bone via TP53INP1 Signaling
por: Xiao, Wei‐Yuan, et al.
Publicado: (2018)

Defects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1
por: Seillier, Marion, et al.
Publicado: (2015)

TP53inp1 Gene Is Implicated in Early Radiation Response in Human Fibroblast Cells
por: Sándor, Nikolett, et al.
Publicado: (2015)

TP53INP1 inhibits hypoxia‐induced vasculogenic mimicry formation via the ROS/snail signalling axis in breast cancer
por: Wang, Yi, et al.
Publicado: (2018)

TP53INP1 exerts neuroprotection under ageing and Parkinson’s disease-related stress condition
por: Dinh, Emilie, et al.
Publicado: (2021)

Downregulation of HMGA1 Mediates Autophagy and Inhibits Migration and Invasion in Bladder Cancer via miRNA-221/TP53INP1/p-ERK Axis
por: Liu, Xiaoqiang, et al.
Publicado: (2020)

TP53INP2 Modulates Epithelial-to-Mesenchymal Transition via the GSK-3β/β-Catenin/Snail1 Pathway in Bladder Cancer Cells
por: Zhou, Zhengtao, et al.
Publicado: (2020)

miR-96 regulates liver tumor-initiating cells expansion by targeting TP53INP1 and predicts Sorafenib resistance
por: Huang, Yonggang, et al.
Publicado: (2020)

LncRNA GAS5-mediated miR-1323 promotes tumor progression by targeting TP53INP1 in hepatocellular carcinoma
por: Zhang, Fengjuan, et al.
Publicado: (2019)

MiR-155-5p accelerates the metastasis of cervical cancer cell via targeting TP53INP1
por: Li, Ning, et al.
Publicado: (2019)

MicroRNA-200a confers chemoresistance by antagonizing TP53INP1 and YAP1 in human breast cancer
por: Yu, San-Jian, et al.
Publicado: (2018)

Impact of Epigenomic Hypermethylation at TP53 on Allogeneic Hematopoietic Cell Transplantation Outcomes for Myelodysplastic Syndromes
por: Wang, Wei, et al.
Publicado: (2021)

Corrigendum: Downregulation of HMGA1 Mediates Autophagy and Inhibits Migration and Invasion in Bladder Cancer via miRNA-221/TP53INP1/p-ERK Axis
por: Liu, Xiaoqiang, et al.
Publicado: (2020)

MLH1 promoter hypermethylation in uterine carcinosarcoma rarely coexists with TP53 mutation
por: Kunc, Michal, et al.
Publicado: (2019)

Downregulation of microRNA-3934-5p induces apoptosis and inhibits the proliferation of neuroblastoma cells by targeting TP53INP1
por: Ye, Wei, et al.
Publicado: (2019)

Somatic intronic TP53 c.375+5G mutations are a recurrent but under‐recognized mode of TP53 inactivation
por: Chui, M Herman, et al.
Publicado: (2021)

Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis
por: Zhou, Yi, et al.
Publicado: (2023)

Development and validation of prognostic model based on extragastric lymph nodes metastasis and lymph node ratio in node-positive gastric cancer: a retrospective cohort study based on a multicenter database
por: Zeng, Yi, et al.
Publicado: (2023)

Overexpression of TP53INP2 Promotes Apoptosis in Clear Cell Renal Cell Cancer via Caspase-8/TRAF6 Signaling Pathway
por: Li, Xunjia, et al.
Publicado: (2022)

Downregulation of miR-3934-5p enhances A549 cell sensitivity to cisplatin by targeting TP53INP1
por: Ren, Aijun, et al.
Publicado: (2019)

Pleiotropic Functions for Transcription Factor Zscan10
por: Kraus, Petra, et al.
Publicado: (2014)

LncRNA NR_027471 Functions as a ceRNA for miRNA-8055 Leading to Suppression of Osteosarcoma by Regulating the Expression of TP53INP1
por: Chen, Jiajia, et al.
Publicado: (2020)

MGMT promoter hypermethylation is a frequent, early, and consistent event in astrocytoma progression, and not correlated with TP53 mutation
por: Groenendijk, Floris H., et al.
Publicado: (2010)

Associations among smoking, MGMT hypermethylation, TP53-mutations, and relapse in head and neck squamous cell carcinoma
por: Matsuda, Shinichi, et al.
Publicado: (2020)

Promoter Hypermethylation-mediated Inactivation of LRRC4 in Gliomas
por: Zhang, Zuping, et al.
Publicado: (2008)

Zscan4c activates endogenous retrovirus MERVL and cleavage embryo genes
por: Zhang, Weiyu, et al.
Publicado: (2019)

ZSCAN1 Autoantibodies Are Associated with Pediatric Paraneoplastic ROHHAD
por: Mandel‐Brehm, Caleigh, et al.
Publicado: (2022)

MicroRNA-155-5p Contributes to 5-Fluorouracil Resistance Through Down-Regulating TP53INP1 in Oral Squamous Cell Carcinoma
por: Liu, Bowen, et al.
Publicado: (2022)

Long noncoding RNA TCONS_00026334 is involved in suppressing the progression of colorectal cancer by regulating miR‑548n/TP53INP1 signaling pathway
por: Zhu, Mingming, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_7fqkf2ejb0gem576m1mcca9hpi