FASN multi-omic characterization reveals metabolic heterogeneity in pancreatic and prostate adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) and prostate cancer (PCa) are among the most prevalent malignant tumors worldwide. There is now a comprehensive understanding of metabolic reprogramming as a hallmark of cancer. Fatty acid synthase (FASN) is a key regulator of the lipid metabolic n...

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Detalles Bibliográficos
Autores principales: Chianese, Ugo, Papulino, Chiara, Ali, Ahmad, Ciardiello, Fortunato, Cappabianca, Salvatore, Altucci, Lucia, Carafa, Vincenzo, Benedetti, Rosaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847120/
https://www.ncbi.nlm.nih.gov/pubmed/36650542
http://dx.doi.org/10.1186/s12967-023-03874-5

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