Hypoxia induces transgenerational epigenetic inheritance of small RNAs

Animals sense and adapt to decreased oxygen availability, but whether and how hypoxia exposure in ancestors can elicit phenotypic consequences in normoxia-reared descendants are unclear. We show that hypoxia educes an intergenerational reduction in lipids and a transgenerational reduction in fertili...

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Detalles Bibliográficos
Autores principales: Wang, Simon Yuan, Kim, Kathleen, O’Brown, Zach Klapholz, Levan, Aileen, Dodson, Anne Elizabeth, Kennedy, Scott G., Chernoff, Chaim, Greer, Eric Lieberman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847139/
https://www.ncbi.nlm.nih.gov/pubmed/36516753
http://dx.doi.org/10.1016/j.celrep.2022.111800

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