Cargando…

Sustained postconfluent culture of human mammary epithelial cells enriches for luminal and c-Kit+ subtypes

BACKGROUND: A challenge in human mammary epithelial cell (HMEC) culture is sustaining the representation of competing luminal, myoepithelial, and progenitor lineages over time. As cells replicate in culture, myoepithelial cells come to dominate the composition of the culture with serial passaging. T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Todhunter, Michael E., Miyano, Masaru, Carlson, Eric G., Hinz, Stefan, LaBarge, Mark A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847146/ https://www.ncbi.nlm.nih.gov/pubmed/36653787 http://dx.doi.org/10.1186/s13058-022-01595-z

Ejemplares similares

Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells
por: Senapati, Parijat, et al.
Publicado: (2023)

Volume-constrained microcontainers enable myoepithelial functional differentiation in highly parallel mammary organoid culture
por: Todhunter, Michael E., et al.
Publicado: (2021)

Age and the means of bypassing stasis influence the intrinsic subtype of immortalized human mammary epithelial cells
por: Lee, Jonathan K., et al.
Publicado: (2015)

Deep proteome profiling of human mammary epithelia at lineage and age resolution
por: Hinz, Stefan, et al.
Publicado: (2021)

Age-related gene expression in luminal epithelial cells is driven by a microenvironment made from myoepithelial cells
por: Miyano, Masaru, et al.
Publicado: (2017)

Protocol for computationally evaluating the loss of stoichiometry and coordinated expression of proteins
por: Hinz, Stefan, et al.
Publicado: (2022)

Evidence for accelerated aging in mammary epithelia of women carrying germline BRCA1 or BRCA2 mutations
por: Shalabi, Sundus F., et al.
Publicado: (2021)

Growth, morphology and chemosensitivity studies on postconfluent cells cultured in 'V'-bottomed microtiter plates.
por: Pizao, P. E., et al.
Publicado: (1992)

Different culture media modulate growth, heterogeneity, and senescence in human mammary epithelial cell cultures
por: Lee, Jonathan K., et al.
Publicado: (2018)

An antiproliferative heparan sulfate species produced by postconfluent smooth muscle cells
Publicado: (1985)

Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance
por: Jokela, Tiina A., et al.
Publicado: (2018)

Aging phenotypes in cultured normal human mammary epithelial cells are correlated with decreased telomerase activity independent of telomere length
por: Sputova, Klara, et al.
Publicado: (2013)

TGF-β–Mediated Modulation of Cell–Cell Interactions in Postconfluent Maturing Corneal Endothelial Cells
por: Santerre, Kim, et al.
Publicado: (2022)

Lesion complexity drives age related cancer susceptibility in human mammary epithelial cells
por: Sridharan, Deepa M., et al.
Publicado: (2017)

Probing the luminal microenvironment of reconstituted epithelial microtissues
por: Cerchiari, Alec E., et al.
Publicado: (2016)

Id-1 is not expressed in the luminal epithelial cells of mammary glands
por: Uehara, Norihisa, et al.
Publicado: (2003)

TFAP2C Governs the Luminal Epithelial Phenotype in Mammary Development and Carcinogenesis
por: Cyr, Anthony R, et al.
Publicado: (2014)

VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland
por: Smith, Prestina, et al.
Publicado: (2019)

Opportunities for organoids as new models of aging
por: Hu, Jennifer L., et al.
Publicado: (2018)

Delayed γH2AX foci disappearance in mammary epithelial cells from aged women reveals an age-associated DNA repair defect
por: Anglada, Teresa, et al.
Publicado: (2019)

Annexin A8 Identifies a Subpopulation of Transiently Quiescent c-Kit Positive Luminal Progenitor Cells of the Ductal Mammary Epithelium
por: Iglesias, Juan Manuel, et al.
Publicado: (2015)

A Long-Lived Luminal Subpopulation Enriched with Alveolar Progenitors Serves as Cellular Origin of Heterogeneous Mammary Tumors
por: Tao, Luwei, et al.
Publicado: (2015)

Paracrine Met signaling triggers epithelial–mesenchymal transition in mammary luminal progenitors, affecting their fate
por: Di-Cicco, Amandine, et al.
Publicado: (2015)

Highly metastatic claudin-low mammary cancers can originate from luminal epithelial cells
por: Rädler, Patrick D., et al.
Publicado: (2021)

CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells
por: Sleeman, Katherine E, et al.
Publicado: (2006)

Defining the clinical characteristics of mammary analog secretory carcinoma of the salivary gland: Analysis of the National Cancer Database
por: Patel, Akshilkumar, et al.
Publicado: (2023)

Histone Variant H2A.J Is Enriched in Luminal Epithelial Gland Cells
por: Redon, Christophe E., et al.
Publicado: (2021)

Two functionally distinct epithelial progenitors exist within the luminal cell compartment of the mouse mammary gland
por: Stingl, J, et al.
Publicado: (2008)

Luminal Epithelial Cells within the Mammary Gland Can Produce Basal Cells upon Oncogenic Stress
por: Hein, Sarah M., et al.
Publicado: (2015)

Bovine mammary epithelial cell cultures for the study of mammary gland functions
por: Jedrzejczak, Magdalena, et al.
Publicado: (2013)

Single luminal epithelial progenitors can generate prostate organoids in culture
por: Chua, Chee Wai, et al.
Publicado: (2014)

Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo
por: Sonzogni, Olmo, et al.
Publicado: (2018)

Mammary Tumor Organoid Culture in Non‐Adhesive Alginate for Luminal Mechanics and High‐Throughput Drug Screening
por: Fang, Guocheng, et al.
Publicado: (2021)

To grow mouse mammary epithelial cells in culture
Publicado: (1984)

A mouse model for Luminal epithelial like ER positive subtype of human breast cancer
por: Kumar, MJ Mahesh, et al.
Publicado: (2007)

The induction of apoptosis in human mammary luminal epithelial cells by expression of activated c-neu and its abrogation by glucocorticoids.
por: Harris, R. A., et al.
Publicado: (1995)

TOX3 is expressed in mammary ER(+) epithelial cells and regulates ER target genes in luminal breast cancer
por: Seksenyan, Akop, et al.
Publicado: (2015)

Processing of Human Reduction Mammoplasty and Mastectomy Tissues for Cell Culture
por: LaBarge, Mark A., et al.
Publicado: (2013)

Immortalization of normal human mammary epithelial cells in two steps by direct targeting of senescence barriers does not require gross genomic alterations
por: Garbe, James C, et al.
Publicado: (2014)

Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland
por: Shehata, Mona, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_e4brsrg3qhcgehgacje99cp41c