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Developability assessment at early-stage discovery to enable development of antibody-derived therapeutics
Developability refers to the likelihood that an antibody candidate will become a manufacturable, safe and efficacious drug. Although the safety and efficacy of a drug candidate will be well considered by sponsors and regulatory agencies, developability in the narrow sense can be defined as the likel...
Autores principales: | Zhang, Weijie, Wang, Hao, Feng, Nan, Li, Yifeng, Gu, Jijie, Wang, Zhuozhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847343/ https://www.ncbi.nlm.nih.gov/pubmed/36683767 http://dx.doi.org/10.1093/abt/tbac029 |
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