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Adjuvant Abemaciclib Combined with Endocrine Therapy: Efficacy Results in monarchE Cohort 1
The monarchE Cohort 1 patient population was enrolled based on high-risk clinicopathological features that can easily be identified as part of routine clinical breast cancer evaluation. Efficacy data from Cohort 1 demonstrate substantial evidence of benefit for adjuvant abemaciclib+ET in patients wi...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847542/ https://www.ncbi.nlm.nih.gov/pubmed/36342342 http://dx.doi.org/10.1093/oncolo/oyac234 |
| _version_ | 1784871478462775296 |
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| author | Toi, Masakazu Boyle, Frances Im, Young-Hyuck Reinisch, Mattea Molthrop, David Jiang, Zefei Wei, Ran Sapunar, Francisco Grimes, Brenda R Nabinger, Sarah Cassidy Johnston, Stephen R D |
| author_facet | Toi, Masakazu Boyle, Frances Im, Young-Hyuck Reinisch, Mattea Molthrop, David Jiang, Zefei Wei, Ran Sapunar, Francisco Grimes, Brenda R Nabinger, Sarah Cassidy Johnston, Stephen R D |
| author_sort | Toi, Masakazu |
| collection | PubMed |
| description | The monarchE Cohort 1 patient population was enrolled based on high-risk clinicopathological features that can easily be identified as part of routine clinical breast cancer evaluation. Efficacy data from Cohort 1 demonstrate substantial evidence of benefit for adjuvant abemaciclib+ET in patients with HR+, HER2− early breast cancer at high risk of recurrence (ClinicalTrials.gov: NCT03155997 [monarchE]). |
| format | Online Article Text |
| id | pubmed-9847542 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-98475422023-01-20 Adjuvant Abemaciclib Combined with Endocrine Therapy: Efficacy Results in monarchE Cohort 1 Toi, Masakazu Boyle, Frances Im, Young-Hyuck Reinisch, Mattea Molthrop, David Jiang, Zefei Wei, Ran Sapunar, Francisco Grimes, Brenda R Nabinger, Sarah Cassidy Johnston, Stephen R D Oncologist Brief Communication The monarchE Cohort 1 patient population was enrolled based on high-risk clinicopathological features that can easily be identified as part of routine clinical breast cancer evaluation. Efficacy data from Cohort 1 demonstrate substantial evidence of benefit for adjuvant abemaciclib+ET in patients with HR+, HER2− early breast cancer at high risk of recurrence (ClinicalTrials.gov: NCT03155997 [monarchE]). Oxford University Press 2022-11-07 /pmc/articles/PMC9847542/ /pubmed/36342342 http://dx.doi.org/10.1093/oncolo/oyac234 Text en © The Author(s) 2022. Published by Oxford University Press. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
| spellingShingle | Brief Communication Toi, Masakazu Boyle, Frances Im, Young-Hyuck Reinisch, Mattea Molthrop, David Jiang, Zefei Wei, Ran Sapunar, Francisco Grimes, Brenda R Nabinger, Sarah Cassidy Johnston, Stephen R D Adjuvant Abemaciclib Combined with Endocrine Therapy: Efficacy Results in monarchE Cohort 1 |
| title | Adjuvant Abemaciclib Combined with Endocrine Therapy: Efficacy Results in monarchE Cohort 1 |
| title_full | Adjuvant Abemaciclib Combined with Endocrine Therapy: Efficacy Results in monarchE Cohort 1 |
| title_fullStr | Adjuvant Abemaciclib Combined with Endocrine Therapy: Efficacy Results in monarchE Cohort 1 |
| title_full_unstemmed | Adjuvant Abemaciclib Combined with Endocrine Therapy: Efficacy Results in monarchE Cohort 1 |
| title_short | Adjuvant Abemaciclib Combined with Endocrine Therapy: Efficacy Results in monarchE Cohort 1 |
| title_sort | adjuvant abemaciclib combined with endocrine therapy: efficacy results in monarche cohort 1 |
| topic | Brief Communication |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847542/ https://www.ncbi.nlm.nih.gov/pubmed/36342342 http://dx.doi.org/10.1093/oncolo/oyac234 |
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