Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination

RNA vaccines are efficient preventive measures to combat the SARS-CoV-2 pandemic. High levels of neutralizing SARS-CoV-2-antibodies are an important component of vaccine-induced immunity. Shortly after the initial two mRNA vaccine doses, the IgG response mainly consists of the pro-inflammatory subcl...

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Detalles Bibliográficos
Autores principales: Irrgang, Pascal, Gerling, Juliane, Kocher, Katharina, Lapuente, Dennis, Steininger, Philipp, Habenicht, Katharina, Wytopil, Monika, Beileke, Stephanie, Schäfer, Simon, Zhong, Jahn, Ssebyatika, George, Krey, Thomas, Falcone, Valeria, Schülein, Christine, Peter, Antonia Sophia, Nganou-Makamdop, Krystelle, Hengel, Hartmut, Held, Jürgen, Bogdan, Christian, Überla, Klaus, Schober, Kilian, Winkler, Thomas H., Tenbusch, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847566/
https://www.ncbi.nlm.nih.gov/pubmed/36548397
http://dx.doi.org/10.1126/sciimmunol.ade2798

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