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Catalytic photochemical enantioselective α-alkylation with pyridinium salts

We have developed a chiral amine catalyzed enantioselective α-alkylation of aldehydes with amino acid derived pyridinium salts as alkylating reagents. The reaction proceeds in the presence of visible light and in the absence of a photocatalyst via a light activated charge-transfer complex. We apply...

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Detalles Bibliográficos
Autores principales: Yetra, Santhivardhana Reddy, Schmitt, Nathan, Tambar, Uttam K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847668/
https://www.ncbi.nlm.nih.gov/pubmed/36741522
http://dx.doi.org/10.1039/d2sc05654b