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Flame resistant cotton lines generated by synergistic epistasis in a MAGIC population

Textiles made from cotton fibers are flammable and thus often include flame retardant additives for consumer safety. Transgressive segregation in multi-parent populations facilitates new combinations of alleles of genes and can result in traits that are superior to those of any of the parents. A scr...

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Autores principales: Thyssen, Gregory N., Condon, Brian D., Hinchliffe, Doug J., Zeng, Linghe, Naoumkina, Marina, Jenkins, Johnie N., McCarty, Jack C., Sui, Ruixiu, Madison, Crista, Li, Ping, Fang, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847967/
https://www.ncbi.nlm.nih.gov/pubmed/36652412
http://dx.doi.org/10.1371/journal.pone.0278696
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author Thyssen, Gregory N.
Condon, Brian D.
Hinchliffe, Doug J.
Zeng, Linghe
Naoumkina, Marina
Jenkins, Johnie N.
McCarty, Jack C.
Sui, Ruixiu
Madison, Crista
Li, Ping
Fang, David D.
author_facet Thyssen, Gregory N.
Condon, Brian D.
Hinchliffe, Doug J.
Zeng, Linghe
Naoumkina, Marina
Jenkins, Johnie N.
McCarty, Jack C.
Sui, Ruixiu
Madison, Crista
Li, Ping
Fang, David D.
author_sort Thyssen, Gregory N.
collection PubMed
description Textiles made from cotton fibers are flammable and thus often include flame retardant additives for consumer safety. Transgressive segregation in multi-parent populations facilitates new combinations of alleles of genes and can result in traits that are superior to those of any of the parents. A screen of 257 recombinant inbred lines from a multi-parent advanced generation intercross (MAGIC) population for naturally enhance flame retardance (FR) was conducted. All eleven parents, like all conventional white fiber cotton cultivars produce flammable fabric. MAGIC recombinant inbred lines (RILs) that produced fibers with significantly lower heat release capacities (HRC) as measured by microscale combustion calorimetry (MCC) were identified and the stability of the phenotypes of the outliers were confirmed when the RILs were grown at an additional location. Of the textiles fabricated from the five superior RILs, four exhibited the novel characteristic of inherent flame resistance. When exposed to open flame by standard 45° incline flammability testing, these four fabrics self-extinguished. To determine the genetic architecture of this novel trait, linkage, epistatic and multi-locus genome wide association studies (GWAS) were conducted with 473k SNPs identified by whole genome sequencing (WGS). Transcriptomes of developing fiber cells from select RILs were sequenced (RNAseq). Together, these data provide insight into the genetic mechanism of the unexpected emergence of flame-resistant cotton by transgressive segregation in a breeding program. The incorporation of this trait into global cotton germplasm by breeding has the potential to greatly reduce the costs and impacts of flame-retardant chemicals.
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spelling pubmed-98479672023-01-19 Flame resistant cotton lines generated by synergistic epistasis in a MAGIC population Thyssen, Gregory N. Condon, Brian D. Hinchliffe, Doug J. Zeng, Linghe Naoumkina, Marina Jenkins, Johnie N. McCarty, Jack C. Sui, Ruixiu Madison, Crista Li, Ping Fang, David D. PLoS One Research Article Textiles made from cotton fibers are flammable and thus often include flame retardant additives for consumer safety. Transgressive segregation in multi-parent populations facilitates new combinations of alleles of genes and can result in traits that are superior to those of any of the parents. A screen of 257 recombinant inbred lines from a multi-parent advanced generation intercross (MAGIC) population for naturally enhance flame retardance (FR) was conducted. All eleven parents, like all conventional white fiber cotton cultivars produce flammable fabric. MAGIC recombinant inbred lines (RILs) that produced fibers with significantly lower heat release capacities (HRC) as measured by microscale combustion calorimetry (MCC) were identified and the stability of the phenotypes of the outliers were confirmed when the RILs were grown at an additional location. Of the textiles fabricated from the five superior RILs, four exhibited the novel characteristic of inherent flame resistance. When exposed to open flame by standard 45° incline flammability testing, these four fabrics self-extinguished. To determine the genetic architecture of this novel trait, linkage, epistatic and multi-locus genome wide association studies (GWAS) were conducted with 473k SNPs identified by whole genome sequencing (WGS). Transcriptomes of developing fiber cells from select RILs were sequenced (RNAseq). Together, these data provide insight into the genetic mechanism of the unexpected emergence of flame-resistant cotton by transgressive segregation in a breeding program. The incorporation of this trait into global cotton germplasm by breeding has the potential to greatly reduce the costs and impacts of flame-retardant chemicals. Public Library of Science 2023-01-18 /pmc/articles/PMC9847967/ /pubmed/36652412 http://dx.doi.org/10.1371/journal.pone.0278696 Text en https://creativecommons.org/publicdomain/zero/1.0/This is an open access article, free of all copyright, and may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose. The work is made available under the Creative Commons CC0 (https://creativecommons.org/publicdomain/zero/1.0/) public domain dedication.
spellingShingle Research Article
Thyssen, Gregory N.
Condon, Brian D.
Hinchliffe, Doug J.
Zeng, Linghe
Naoumkina, Marina
Jenkins, Johnie N.
McCarty, Jack C.
Sui, Ruixiu
Madison, Crista
Li, Ping
Fang, David D.
Flame resistant cotton lines generated by synergistic epistasis in a MAGIC population
title Flame resistant cotton lines generated by synergistic epistasis in a MAGIC population
title_full Flame resistant cotton lines generated by synergistic epistasis in a MAGIC population
title_fullStr Flame resistant cotton lines generated by synergistic epistasis in a MAGIC population
title_full_unstemmed Flame resistant cotton lines generated by synergistic epistasis in a MAGIC population
title_short Flame resistant cotton lines generated by synergistic epistasis in a MAGIC population
title_sort flame resistant cotton lines generated by synergistic epistasis in a magic population
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847967/
https://www.ncbi.nlm.nih.gov/pubmed/36652412
http://dx.doi.org/10.1371/journal.pone.0278696
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