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Tefillin use induces preconditioning associated changes in heart rate variability

Short bouts of occlusion of blood flow can induce a preconditioning response that reduces subsequent damage from longer periods of ischemia. It has been shown that ischemic preconditioning (IPC) can be elicited remotely (RIPC) through limitation of blood flow and as recently described via only pain...

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Autores principales: Koch, Sheryl E., Martin, Elyse, Verma, Amitesh, Adjei, Stacey, Rubinstein, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847972/
https://www.ncbi.nlm.nih.gov/pubmed/36652449
http://dx.doi.org/10.1371/journal.pone.0280216
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author Koch, Sheryl E.
Martin, Elyse
Verma, Amitesh
Adjei, Stacey
Rubinstein, Jack
author_facet Koch, Sheryl E.
Martin, Elyse
Verma, Amitesh
Adjei, Stacey
Rubinstein, Jack
author_sort Koch, Sheryl E.
collection PubMed
description Short bouts of occlusion of blood flow can induce a preconditioning response that reduces subsequent damage from longer periods of ischemia. It has been shown that ischemic preconditioning (IPC) can be elicited remotely (RIPC) through limitation of blood flow and as recently described via only pain sensation. Non-obstructive banding (NOB) through the donning of tefillin (a box with sacred texts attached to a leather strap that is traditionally bound to the non-dominant arm of Jewish adults during morning prayers) has been shown to elicit an RIPC response at least partially through pain sensation. This study evaluated the effects of NOB on heart rate variability (HRV) dependent factors that are known to be affected by various RIPC stimuli. We recruited 30 healthy subjects and subjected them to NOB versus control and found various HRV markers associated with RIPC to be changed in the NOB group. This finding provides further evidence that tefillin, likely through NOB induced RIPC changes, may still be a viable clinical pathway to prevent and decrease the morbidity associated with ischemic events.
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spelling pubmed-98479722023-01-19 Tefillin use induces preconditioning associated changes in heart rate variability Koch, Sheryl E. Martin, Elyse Verma, Amitesh Adjei, Stacey Rubinstein, Jack PLoS One Research Article Short bouts of occlusion of blood flow can induce a preconditioning response that reduces subsequent damage from longer periods of ischemia. It has been shown that ischemic preconditioning (IPC) can be elicited remotely (RIPC) through limitation of blood flow and as recently described via only pain sensation. Non-obstructive banding (NOB) through the donning of tefillin (a box with sacred texts attached to a leather strap that is traditionally bound to the non-dominant arm of Jewish adults during morning prayers) has been shown to elicit an RIPC response at least partially through pain sensation. This study evaluated the effects of NOB on heart rate variability (HRV) dependent factors that are known to be affected by various RIPC stimuli. We recruited 30 healthy subjects and subjected them to NOB versus control and found various HRV markers associated with RIPC to be changed in the NOB group. This finding provides further evidence that tefillin, likely through NOB induced RIPC changes, may still be a viable clinical pathway to prevent and decrease the morbidity associated with ischemic events. Public Library of Science 2023-01-18 /pmc/articles/PMC9847972/ /pubmed/36652449 http://dx.doi.org/10.1371/journal.pone.0280216 Text en © 2023 Koch et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Koch, Sheryl E.
Martin, Elyse
Verma, Amitesh
Adjei, Stacey
Rubinstein, Jack
Tefillin use induces preconditioning associated changes in heart rate variability
title Tefillin use induces preconditioning associated changes in heart rate variability
title_full Tefillin use induces preconditioning associated changes in heart rate variability
title_fullStr Tefillin use induces preconditioning associated changes in heart rate variability
title_full_unstemmed Tefillin use induces preconditioning associated changes in heart rate variability
title_short Tefillin use induces preconditioning associated changes in heart rate variability
title_sort tefillin use induces preconditioning associated changes in heart rate variability
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847972/
https://www.ncbi.nlm.nih.gov/pubmed/36652449
http://dx.doi.org/10.1371/journal.pone.0280216
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