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Characterizing inhibitors of human AP endonuclease 1

AP endonuclease 1 (APE1) processes DNA lesions including apurinic/apyrimidinic sites and 3´-blocking groups, mediating base excision repair and single strand break repair. Much effort has focused on developing specific inhibitors of APE1, which could have important applications in basic research and...

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Detalles Bibliográficos
Autores principales:	Pidugu, Lakshmi S., Servius, Hardler W., Sevdalis, Spiridon E., Cook, Mary E., Varney, Kristen M., Pozharski, Edwin, Drohat, Alexander C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9847973/ https://www.ncbi.nlm.nih.gov/pubmed/36652434 http://dx.doi.org/10.1371/journal.pone.0280526

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