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Precision Effects of Glibenclamide on MRI Endophenotypes in Clinically Relevant Murine Traumatic Brain Injury
Addressing traumatic brain injury (TBI) heterogeneity is increasingly recognized as essential for therapy translation given the long history of failed clinical trials. We evaluated differential effects of a promising treatment (glibenclamide) based on dose, TBI type (patient selection), and imaging...
Autores principales: | Zusman, Benjamin E., Wu, Yijen, Kochanek, Patrick M., Vagni, Vincent E., Janesko-Feldman, Keri, Gerzanich, Volodymyr, Simard, J. Marc, Karahalios, Katherine, Mihaljevic, Sandra, Raikwar, Sudhanshu, Rani, Anupama, Rulney, Jarrod, Desai, Shashvat M., Catapano, Joshua, Jha, Ruchira M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848216/ https://www.ncbi.nlm.nih.gov/pubmed/36661464 http://dx.doi.org/10.1097/CCM.0000000000005749 |
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