Precision Effects of Glibenclamide on MRI Endophenotypes in Clinically Relevant Murine Traumatic Brain Injury

Addressing traumatic brain injury (TBI) heterogeneity is increasingly recognized as essential for therapy translation given the long history of failed clinical trials. We evaluated differential effects of a promising treatment (glibenclamide) based on dose, TBI type (patient selection), and imaging...

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Detalles Bibliográficos
Autores principales: Zusman, Benjamin E., Wu, Yijen, Kochanek, Patrick M., Vagni, Vincent E., Janesko-Feldman, Keri, Gerzanich, Volodymyr, Simard, J. Marc, Karahalios, Katherine, Mihaljevic, Sandra, Raikwar, Sudhanshu, Rani, Anupama, Rulney, Jarrod, Desai, Shashvat M., Catapano, Joshua, Jha, Ruchira M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848216/
https://www.ncbi.nlm.nih.gov/pubmed/36661464
http://dx.doi.org/10.1097/CCM.0000000000005749

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