Cargando…

Investigation of novel alkyl/benzyl (4-sulphamoylphenyl)carbamimidothioates as carbonic anhydrase inhibitors

A library of novel alkyl/benzyl (4-sulphamoylphenyl)carbamimidothioates was synthesised by selective S-alkylation of the easily accessible 4-thioureidobenzenesulphonamide. The compounds were assayed as inhibitors of four human (h) carbonic anhydrase isoforms hCA I, II, VII, and XIII, as well as thre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Abdoli, Morteza, Bonardi, Alessandro, Supuran, Claudiu T., Žalubovskis, Raivis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848269/ https://www.ncbi.nlm.nih.gov/pubmed/36629134 http://dx.doi.org/10.1080/14756366.2022.2152811

Ejemplares similares

4-(3-Alkyl/benzyl-guanidino)benzenesulfonamides as selective carbonic anhydrase VII inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2022)

4-Cyanamidobenzenesulfonamide derivatives: a novel class of human and bacterial carbonic anhydrase inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2022)

Novel thiazolone-benzenesulphonamide inhibitors of human and bacterial carbonic anhydrases
por: Abdoli, Morteza, et al.
Publicado: (2023)

2-((1H-Benzo[d]imidazol-2-yl)amino)benzo[d]thiazole-6-sulphonamides: a class of carbonic anhydrase II and VII-selective inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2023)

1,2,3-Benzoxathiazine-2,2-dioxides – effective inhibitors of human carbonic anhydrases
por: Ivanova, Jekaterina, et al.
Publicado: (2022)

Inhibition Studies on Human and Mycobacterial Carbonic Anhydrases with N-((4-Sulfamoylphenyl)carbamothioyl) Amides
por: Abdoli, Morteza, et al.
Publicado: (2023)

Benzenesulfonamides Incorporating Hydantoin Moieties Effectively Inhibit Eukaryoticand Human Carbonic Anhydrases
por: Abdoli, Morteza, et al.
Publicado: (2022)

The antibiotic furagin and its derivatives are isoform-selective human carbonic anhydrase inhibitors
por: Pustenko, Aleksandrs, et al.
Publicado: (2020)

Derivatives of 4-methyl-1,2,3-benzoxathiazine 2,2-dioxide as selective inhibitors of human carbonic anhydrases IX and XII over the cytosolic isoforms I and II
por: Ivanova, Jekaterīna, et al.
Publicado: (2023)

3H-1,2-Benzoxaphosphepine 2-oxides as selective inhibitors of carbonic anhydrase IX and XII
por: Pustenko, Aleksandrs, et al.
Publicado: (2022)

Sulfocoumarins as dual inhibitors of human carbonic anhydrase isoforms IX/XII and of human thioredoxin reductase
por: Krasavin, Mikhail, et al.
Publicado: (2020)

Aryl derivatives of 3H-1,2-benzoxathiepine 2,2-dioxide as carbonic anhydrase inhibitors
por: Pustenko, Aleksandrs, et al.
Publicado: (2019)

Aryl derivatives of 3H-1,2-benzoxaphosphepine 2-oxides as inhibitors of cancer-related carbonic anhydrase isoforms IX and XII
por: Balašova, Anastasija, et al.
Publicado: (2023)

7-Acylamino-3H-1,2-benzoxathiepine 2,2-dioxides as new isoform-selective carbonic anhydrase IX and XII inhibitors
por: Pustenko, Aleksandrs, et al.
Publicado: (2020)

3H-1,2-benzoxathiepine 2,2-dioxides: a new class of isoform-selective carbonic anhydrase inhibitors
por: Pustenko, Aleksandrs, et al.
Publicado: (2017)

Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase
por: Nocentini, Alessio, et al.
Publicado: (2021)

Benzamide-4-Sulfonamides Are Effective Human Carbonic Anhydrase I, II, VII, and IX Inhibitors
por: Abdoli, Morteza, et al.
Publicado: (2018)

Hydrophobic Substituents of the Phenylmethylsulfamide Moiety Can Be Used for the Development of New Selective Carbonic Anhydrase Inhibitors
por: De Simone, Giuseppina, et al.
Publicado: (2014)

Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivative
por: Bibi, David, et al.
Publicado: (2019)

Combining carbonic anhydrase and thioredoxin reductase inhibitory motifs within a single molecule dramatically increases its cytotoxicity
por: Krasavin, Mikhail, et al.
Publicado: (2020)

Isocoumarins: a new class of selective carbonic anhydrase IX and XII inhibitors
por: Onyılmaz, Mehmet, et al.
Publicado: (2022)

Carbonic Anhydrase Inhibitors Targeting Metabolism and Tumor Microenvironment
por: Angeli, Andrea, et al.
Publicado: (2020)

Discovery of the first-in-class potent and isoform-selective human carbonic anhydrase III inhibitors
por: Giovannuzzi, Simone, et al.
Publicado: (2023)

Inhibition studies of the protozoan α-carbonic anhydrase from Trypanosoma cruzi with phenols
por: Bonardi, Alessandro, et al.
Publicado: (2022)

Diversely N-substituted benzenesulfonamides dissimilarly bind to human carbonic anhydrases: crystallographic investigations of N-nitrosulfonamides
por: Angeli, Andrea, et al.
Publicado: (2023)

Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors
por: Peerzada, Mudasir Nabi, et al.
Publicado: (2023)

Novel insights on saccharin- and acesulfame-based carbonic anhydrase inhibitors: design, synthesis, modelling investigations and biological activity evaluation
por: Guglielmi, Paolo, et al.
Publicado: (2020)

Multivalent Carbonic Anhydrases Inhibitors †
por: Carta, Fabrizio, et al.
Publicado: (2019)

Phenols and Polyphenols as Carbonic Anhydrase Inhibitors
por: Karioti, Anastasia, et al.
Publicado: (2016)

Coumarin carbonic anhydrase inhibitors from natural sources
por: Supuran, Claudiu T.
Publicado: (2020)

Experimental Carbonic Anhydrase Inhibitors for the Treatment of Hypoxic Tumors
por: Supuran, Claudiu T
Publicado: (2020)

Anti-obesity carbonic anhydrase inhibitors: challenges and opportunities
por: Supuran, Claudiu T.
Publicado: (2022)

Carbonic Anhydrase Inhibitors from Marine Natural Products
por: Supuran, Claudiu T.
Publicado: (2022)

Steroids interfere with human carbonic anhydrase activity by using alternative binding mechanisms
por: Nocentini, Alessio, et al.
Publicado: (2018)

Carbonic Anhydrases and Metabolism
por: Supuran, Claudiu T.
Publicado: (2018)

Thienothiopyransulfonamides as Complexing Agents for the Preparation of Dual Carbonic Anhydrase Inhibitors
por: Supuran, Claudiu T.
Publicado: (1995)

Carbon- versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors?
por: Supuran, Claudiu T.
Publicado: (2018)

Selenium-analogs based on natural sources as cancer-associated carbonic anhydrase isoforms IX and XII inhibitors
por: Astrain-Redin, Nora, et al.
Publicado: (2023)

Five-Membered Heterocyclic Sulfonamides as Carbonic Anhydrase Inhibitors
por: Angeli, Andrea, et al.
Publicado: (2023)

Click chemistry approaches for developing carbonic anhydrase inhibitors and their applications
por: Angeli, Andrea, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_i8g0g4d1f3pnfgkd0bughapftl