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Simultaneous administration of EZH2 and BET inhibitors inhibits proliferation and clonogenic ability of metastatic prostate cancer cells

Androgen deprivation therapy (ADT) is a common treatment for recurrent prostate cancer (PC). However, after a certain period of responsiveness, ADT resistance occurs virtually in all patients and the disease progresses to lethal metastatic castration-resistant prostate cancer (mCRPC). Aberrant expre...

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Detalles Bibliográficos
Autores principales: Negri, Aide, Marozzi, Marina, Trisciuoglio, Daniela, Rotili, Dante, Mai, Antonello, Rizzi, Federica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848337/
https://www.ncbi.nlm.nih.gov/pubmed/36629431
http://dx.doi.org/10.1080/14756366.2022.2163242