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Using Patient Perspectives to Inform Better Clinical Trial Design and Conduct: Current Trends and Future Directions
The approach to patient engagement (PE) in drug development has changed rapidly due to many factors, including the complexity of innovative drugs and the need to demonstrate outcomes of relevance to patients, the desire to show ‘value add’ of PE, and the pandemic-related changes to how clinical tria...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848715/ https://www.ncbi.nlm.nih.gov/pubmed/36653601 http://dx.doi.org/10.1007/s40290-022-00458-4 |
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author | Faulkner, Stuart D. Somers, Fabian Boudes, Mathieu Nafria, Begõna Robinson, Paul |
author_facet | Faulkner, Stuart D. Somers, Fabian Boudes, Mathieu Nafria, Begõna Robinson, Paul |
author_sort | Faulkner, Stuart D. |
collection | PubMed |
description | The approach to patient engagement (PE) in drug development has changed rapidly due to many factors, including the complexity of innovative drugs and the need to demonstrate outcomes of relevance to patients, the desire to show ‘value add’ of PE, and the pandemic-related changes to how clinical trials are run, e.g., decentralised studies. In parallel, there have been changes in technology-assisted ways of running clinical trials, capturing patient health outcomes and preferences, an increasing societal demand for diversity and inclusion, and efforts to improve clinical trial efficiency, transparency, and accountability. Organisations are beginning to monitor PE activities and outcomes more effectively to learn and inform future PE strategies. As a result, these factors are facilitating the incorporation of patients’ lived experience, preferences and needs into the design and running of clinical trials more than ever before. In this paper, the authors reflect upon these last few years, the emerging trends and their drivers, and where we may expect PE in clinical research to progress in the near future. |
format | Online Article Text |
id | pubmed-9848715 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-98487152023-01-19 Using Patient Perspectives to Inform Better Clinical Trial Design and Conduct: Current Trends and Future Directions Faulkner, Stuart D. Somers, Fabian Boudes, Mathieu Nafria, Begõna Robinson, Paul Pharmaceut Med Review Article The approach to patient engagement (PE) in drug development has changed rapidly due to many factors, including the complexity of innovative drugs and the need to demonstrate outcomes of relevance to patients, the desire to show ‘value add’ of PE, and the pandemic-related changes to how clinical trials are run, e.g., decentralised studies. In parallel, there have been changes in technology-assisted ways of running clinical trials, capturing patient health outcomes and preferences, an increasing societal demand for diversity and inclusion, and efforts to improve clinical trial efficiency, transparency, and accountability. Organisations are beginning to monitor PE activities and outcomes more effectively to learn and inform future PE strategies. As a result, these factors are facilitating the incorporation of patients’ lived experience, preferences and needs into the design and running of clinical trials more than ever before. In this paper, the authors reflect upon these last few years, the emerging trends and their drivers, and where we may expect PE in clinical research to progress in the near future. Springer International Publishing 2023-01-18 2023 /pmc/articles/PMC9848715/ /pubmed/36653601 http://dx.doi.org/10.1007/s40290-022-00458-4 Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
spellingShingle | Review Article Faulkner, Stuart D. Somers, Fabian Boudes, Mathieu Nafria, Begõna Robinson, Paul Using Patient Perspectives to Inform Better Clinical Trial Design and Conduct: Current Trends and Future Directions |
title | Using Patient Perspectives to Inform Better Clinical Trial Design and Conduct: Current Trends and Future Directions |
title_full | Using Patient Perspectives to Inform Better Clinical Trial Design and Conduct: Current Trends and Future Directions |
title_fullStr | Using Patient Perspectives to Inform Better Clinical Trial Design and Conduct: Current Trends and Future Directions |
title_full_unstemmed | Using Patient Perspectives to Inform Better Clinical Trial Design and Conduct: Current Trends and Future Directions |
title_short | Using Patient Perspectives to Inform Better Clinical Trial Design and Conduct: Current Trends and Future Directions |
title_sort | using patient perspectives to inform better clinical trial design and conduct: current trends and future directions |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9848715/ https://www.ncbi.nlm.nih.gov/pubmed/36653601 http://dx.doi.org/10.1007/s40290-022-00458-4 |
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