The Programmed Death-1 Signaling Axis Modulates Inflammation and LV Structure/Function in a Stress-Induced Cardiomyopathy Model

The role of immune checkpoints in the setting of tissue injury remains unknown. Using an experimental model of isoproterenol (ISO)-induced stress cardiomyopathy, we show that ISO-induced myocardial injury provokes tissue-autonomous up-regulation of the programmed death-1 (PD-1):programmed death liga...

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Detalles Bibliográficos
Autores principales: Hayashi, Tomohiro, Tiwary, Sajal K., Lavine, Kory J., Acharya, Sandeep, Brent, Michael, Adamo, Luigi, Kovacs, Attila, Mann, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research - Preclinical
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849278/
https://www.ncbi.nlm.nih.gov/pubmed/36687266
http://dx.doi.org/10.1016/j.jacbts.2022.05.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849278/
https://www.ncbi.nlm.nih.gov/pubmed/36687266
http://dx.doi.org/10.1016/j.jacbts.2022.05.006

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