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Direct and Indirect Effects of Filamin A on Tau Pathology in Neuronal Cells

In Alzheimer disease (AD), Tau, an axonal microtubule-associated protein, becomes hyperphosphorylated, detaches from microtubules, accumulates, and self-aggregates in the somatodendritic (SD) compartment. The accumulation of hyperphosphorylated and aggregated Tau is also seen in other neurodegenerat...

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Detalles Bibliográficos
Autores principales:	Levert, Stéphanie, Pilliod, Julie, Aumont, Étienne, Armanville, Sandrine, Tremblay, Cyntia, Calon, Frédéric, Leclerc, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849303/ https://www.ncbi.nlm.nih.gov/pubmed/36399251 http://dx.doi.org/10.1007/s12035-022-03121-w

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