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A CRISPR/Cas9-mediated screen identifies determinants of early plasma cell differentiation
INTRODUCTION: The differentiation of B cells into antibody-secreting plasma cells depends on cell division-coupled, epigenetic and other cellular processes that are incompletely understood. METHODS: We have developed a CRISPR/Cas9-based screen that models an early stage of T cell-dependent plasma ce...
Autores principales: | Xiong, Ermeng, Popp, Oliver, Salomon, Claudia, Mertins, Philipp, Kocks, Christine, Rajewsky, Klaus, Chu, Van Trung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849354/ https://www.ncbi.nlm.nih.gov/pubmed/36685499 http://dx.doi.org/10.3389/fimmu.2022.1083119 |
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