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Evolutionary fine-tuning of residual helix structure in disordered proteins manifests in complex structure and lifetime

Transcription depends on complex networks, where folded hub proteins interact with intrinsically disordered transcription factors undergoing coupled folding and binding. For this, local residual structure, a prototypical feature of intrinsic disorder, is key. Here, we dissect the unexplored function...

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Detalles Bibliográficos
Autores principales:	Elkjær, Steffie, Due, Amanda D., Christensen, Lise F., Theisen, Frederik F., Staby, Lasse, Kragelund, Birthe B., Skriver, Karen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849366/ https://www.ncbi.nlm.nih.gov/pubmed/36653471 http://dx.doi.org/10.1038/s42003-023-04445-6

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