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A novel C-terminal modification method enhanced the yield of human papillomavirus L1 or chimeric L1-L2 virus-like particles in the baculovirus system

Human papillomavirus (HPV) major capsid protein L1 virus-like particles (VLPs) produced in the baculovirus system showed excellent safety and immunogenicity, but the relatively high production cost stands as a substantial barrier to extensive commercialization, especially in producing multivalent va...

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Detalles Bibliográficos
Autores principales:	Ma, Mingrao, Xia, Baicheng, Wang, Zhirong, Hao, Yaru, Zhang, Ting, Xu, Xuemei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849392/ https://www.ncbi.nlm.nih.gov/pubmed/36686228 http://dx.doi.org/10.3389/fbioe.2022.1073892

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