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Clustering by antigen-presenting genes reveals immune landscapes and predicts response to checkpoint immunotherapy
Immune checkpoint blockade (ICB) has demonstrated efficacy by reinvigorating immune cytotoxicity against tumors. However, the mechanisms underlying how ICB induces responses in a subset of patients remain unclear. Using bulk and single-cell transcriptomic cohorts of melanoma patients receiving ICB,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849403/ https://www.ncbi.nlm.nih.gov/pubmed/36653470 http://dx.doi.org/10.1038/s41598-023-28167-1 |