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Three Dimensional Lower Extremity Musculoskeletal Geometry of the Visible Human Female and Male

Models and simulations of human function impact medicine and medical technology. Particularly, musculoskeletal modeling provides an avenue for insight into the human body, which might not be otherwise possible. However, reaching the ultimate goal of functional multi-scale human models has been slowe...

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Autores principales: Andreassen, Thor E., Hume, Donald R., Hamilton, Landon D., Walker, Karen E., Higinbotham, Sean E., Shelburne, Kevin B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849470/
https://www.ncbi.nlm.nih.gov/pubmed/36653365
http://dx.doi.org/10.1038/s41597-022-01905-2
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author Andreassen, Thor E.
Hume, Donald R.
Hamilton, Landon D.
Walker, Karen E.
Higinbotham, Sean E.
Shelburne, Kevin B.
author_facet Andreassen, Thor E.
Hume, Donald R.
Hamilton, Landon D.
Walker, Karen E.
Higinbotham, Sean E.
Shelburne, Kevin B.
author_sort Andreassen, Thor E.
collection PubMed
description Models and simulations of human function impact medicine and medical technology. Particularly, musculoskeletal modeling provides an avenue for insight into the human body, which might not be otherwise possible. However, reaching the ultimate goal of functional multi-scale human models has been slowed by the lack of freely available datasets of anatomical models and geometries. Moreover, female-specific geometries have been neglected with a widespread emphasis on male geometry. To help realize this goal, we have developed and shared complete three-dimensional musculoskeletal geometries extracted from the National Libraries of Medicine Visible Human Female and Male cryosections. Muscle, bone, cartilage, ligament, and fat from the pelvis to the ankle were digitized and exported. These geometries provide a foundation for continued work in human musculoskeletal simulation with high-fidelity deformable tissues that enable a better understanding of normal function and the evaluation of pathologies and treatments. This work is novel as it includes both the male and female Visible Human specimens, outputs at multiple levels of post-processing for maximum data reuse, and is publicly available.
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spelling pubmed-98494702023-01-20 Three Dimensional Lower Extremity Musculoskeletal Geometry of the Visible Human Female and Male Andreassen, Thor E. Hume, Donald R. Hamilton, Landon D. Walker, Karen E. Higinbotham, Sean E. Shelburne, Kevin B. Sci Data Data Descriptor Models and simulations of human function impact medicine and medical technology. Particularly, musculoskeletal modeling provides an avenue for insight into the human body, which might not be otherwise possible. However, reaching the ultimate goal of functional multi-scale human models has been slowed by the lack of freely available datasets of anatomical models and geometries. Moreover, female-specific geometries have been neglected with a widespread emphasis on male geometry. To help realize this goal, we have developed and shared complete three-dimensional musculoskeletal geometries extracted from the National Libraries of Medicine Visible Human Female and Male cryosections. Muscle, bone, cartilage, ligament, and fat from the pelvis to the ankle were digitized and exported. These geometries provide a foundation for continued work in human musculoskeletal simulation with high-fidelity deformable tissues that enable a better understanding of normal function and the evaluation of pathologies and treatments. This work is novel as it includes both the male and female Visible Human specimens, outputs at multiple levels of post-processing for maximum data reuse, and is publicly available. Nature Publishing Group UK 2023-01-18 /pmc/articles/PMC9849470/ /pubmed/36653365 http://dx.doi.org/10.1038/s41597-022-01905-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Data Descriptor
Andreassen, Thor E.
Hume, Donald R.
Hamilton, Landon D.
Walker, Karen E.
Higinbotham, Sean E.
Shelburne, Kevin B.
Three Dimensional Lower Extremity Musculoskeletal Geometry of the Visible Human Female and Male
title Three Dimensional Lower Extremity Musculoskeletal Geometry of the Visible Human Female and Male
title_full Three Dimensional Lower Extremity Musculoskeletal Geometry of the Visible Human Female and Male
title_fullStr Three Dimensional Lower Extremity Musculoskeletal Geometry of the Visible Human Female and Male
title_full_unstemmed Three Dimensional Lower Extremity Musculoskeletal Geometry of the Visible Human Female and Male
title_short Three Dimensional Lower Extremity Musculoskeletal Geometry of the Visible Human Female and Male
title_sort three dimensional lower extremity musculoskeletal geometry of the visible human female and male
topic Data Descriptor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849470/
https://www.ncbi.nlm.nih.gov/pubmed/36653365
http://dx.doi.org/10.1038/s41597-022-01905-2
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