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Relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type A aortic dissection

BACKGROUND: Lymphocyte-to-monocyte ratio (LMR) is associated with the mortality of cardiovascular diseases. However, the relationship between preoperative LMR and the prognosis of patients with Stanford type A aortic dissection (TAAD) undergoing surgical treatment remains to be determined. METHODS:...

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Autores principales: Ma, Ming, Zhu, Feng, Fan, Fudong, Pan, Jun, Cao, Hailong, Zhou, Qing, Wang, Dongjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849739/
https://www.ncbi.nlm.nih.gov/pubmed/36684141
http://dx.doi.org/10.3389/fsurg.2022.1103290
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author Ma, Ming
Zhu, Feng
Fan, Fudong
Pan, Jun
Cao, Hailong
Zhou, Qing
Wang, Dongjin
author_facet Ma, Ming
Zhu, Feng
Fan, Fudong
Pan, Jun
Cao, Hailong
Zhou, Qing
Wang, Dongjin
author_sort Ma, Ming
collection PubMed
description BACKGROUND: Lymphocyte-to-monocyte ratio (LMR) is associated with the mortality of cardiovascular diseases. However, the relationship between preoperative LMR and the prognosis of patients with Stanford type A aortic dissection (TAAD) undergoing surgical treatment remains to be determined. METHODS: We enrolled 879 patients with TAAD undergoing surgical treatment between January 2018 and December 2021. Patients were divided into two groups: the Deceased group and the Survived group. The baseline clinical and operative characteristics of the two groups were compared and analyzed. RESULTS: In univariate and multivariate logistic regression analysis, the association between LMR and in-hospital mortality was significant, and LMR (OR = 1.598, 95% CI 1.114–2.485, P = 0.022) remained significant after adjusting for confounders. CONCLUSION: Lower LMR may be independently associated with higher in-hospital mortality in TAAD undergoing surgical treatment.
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spelling pubmed-98497392023-01-20 Relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type A aortic dissection Ma, Ming Zhu, Feng Fan, Fudong Pan, Jun Cao, Hailong Zhou, Qing Wang, Dongjin Front Surg Surgery BACKGROUND: Lymphocyte-to-monocyte ratio (LMR) is associated with the mortality of cardiovascular diseases. However, the relationship between preoperative LMR and the prognosis of patients with Stanford type A aortic dissection (TAAD) undergoing surgical treatment remains to be determined. METHODS: We enrolled 879 patients with TAAD undergoing surgical treatment between January 2018 and December 2021. Patients were divided into two groups: the Deceased group and the Survived group. The baseline clinical and operative characteristics of the two groups were compared and analyzed. RESULTS: In univariate and multivariate logistic regression analysis, the association between LMR and in-hospital mortality was significant, and LMR (OR = 1.598, 95% CI 1.114–2.485, P = 0.022) remained significant after adjusting for confounders. CONCLUSION: Lower LMR may be independently associated with higher in-hospital mortality in TAAD undergoing surgical treatment. Frontiers Media S.A. 2023-01-05 /pmc/articles/PMC9849739/ /pubmed/36684141 http://dx.doi.org/10.3389/fsurg.2022.1103290 Text en © 2023 Ma, Zhu, Fan, Pan, Cao, Zhou and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Surgery
Ma, Ming
Zhu, Feng
Fan, Fudong
Pan, Jun
Cao, Hailong
Zhou, Qing
Wang, Dongjin
Relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type A aortic dissection
title Relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type A aortic dissection
title_full Relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type A aortic dissection
title_fullStr Relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type A aortic dissection
title_full_unstemmed Relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type A aortic dissection
title_short Relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type A aortic dissection
title_sort relationship between preoperative lymphocyte to monocyte ratio and surgery outcome in type a aortic dissection
topic Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849739/
https://www.ncbi.nlm.nih.gov/pubmed/36684141
http://dx.doi.org/10.3389/fsurg.2022.1103290
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