Therapeutic effect of combination vitamin D3 and siponimod on remyelination and modulate microglia activation in cuprizone mouse model of multiple sclerosis

Stimulation of remyelination is critical for the treatment of multiple sclerosis (MS) to alleviate symptoms and protect the myelin sheath from further damage. The current study aimed to investigate the possible therapeutic effects of combining vitamin D3 (Vit D3) and siponimod (Sipo) on enhancing re...

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Detalles Bibliográficos
Autores principales: Al-Otaibi, Kholoud M., Alghamdi, Badrah S., Al-Ghamdi, Maryam A., Mansouri, Rasha A., Ashraf, Ghulam Md, Omar, Ulfat M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Behavioral Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849768/
https://www.ncbi.nlm.nih.gov/pubmed/36688131
http://dx.doi.org/10.3389/fnbeh.2022.1068736

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