Cargando…
Circadian rhythm disruptions: A possible link of bipolar disorder and endocrine comorbidities
Epidemiological studies have demonstrated an association between bipolar disorder (BP) and endocrine diseases. Further, circadian rhythm disruptions may be a potential common pathophysiological mechanism of both disorders. This review provides a brief overview of the molecular mechanisms of circadia...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849950/ https://www.ncbi.nlm.nih.gov/pubmed/36683994 http://dx.doi.org/10.3389/fpsyt.2022.1065754 |
_version_ | 1784872069998051328 |
---|---|
author | Yan, Xiu Xu, Peiwei Sun, Xueli |
author_facet | Yan, Xiu Xu, Peiwei Sun, Xueli |
author_sort | Yan, Xiu |
collection | PubMed |
description | Epidemiological studies have demonstrated an association between bipolar disorder (BP) and endocrine diseases. Further, circadian rhythm disruptions may be a potential common pathophysiological mechanism of both disorders. This review provides a brief overview of the molecular mechanisms of circadian rhythms, as well as roles circadian rhythms play in BP and common endocrine comorbidities such as diabetes and thyroid disease. Treatments targeting the circadian system, both pharmacological and non-pharmacological, are also discussed. The hope is to elicit new interest to the importance of circadian system in BP and offer new entry points and impetus to the development of medicine. |
format | Online Article Text |
id | pubmed-9849950 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98499502023-01-20 Circadian rhythm disruptions: A possible link of bipolar disorder and endocrine comorbidities Yan, Xiu Xu, Peiwei Sun, Xueli Front Psychiatry Psychiatry Epidemiological studies have demonstrated an association between bipolar disorder (BP) and endocrine diseases. Further, circadian rhythm disruptions may be a potential common pathophysiological mechanism of both disorders. This review provides a brief overview of the molecular mechanisms of circadian rhythms, as well as roles circadian rhythms play in BP and common endocrine comorbidities such as diabetes and thyroid disease. Treatments targeting the circadian system, both pharmacological and non-pharmacological, are also discussed. The hope is to elicit new interest to the importance of circadian system in BP and offer new entry points and impetus to the development of medicine. Frontiers Media S.A. 2023-01-05 /pmc/articles/PMC9849950/ /pubmed/36683994 http://dx.doi.org/10.3389/fpsyt.2022.1065754 Text en Copyright © 2023 Yan, Xu and Sun. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Psychiatry Yan, Xiu Xu, Peiwei Sun, Xueli Circadian rhythm disruptions: A possible link of bipolar disorder and endocrine comorbidities |
title | Circadian rhythm disruptions: A possible link of bipolar disorder and endocrine comorbidities |
title_full | Circadian rhythm disruptions: A possible link of bipolar disorder and endocrine comorbidities |
title_fullStr | Circadian rhythm disruptions: A possible link of bipolar disorder and endocrine comorbidities |
title_full_unstemmed | Circadian rhythm disruptions: A possible link of bipolar disorder and endocrine comorbidities |
title_short | Circadian rhythm disruptions: A possible link of bipolar disorder and endocrine comorbidities |
title_sort | circadian rhythm disruptions: a possible link of bipolar disorder and endocrine comorbidities |
topic | Psychiatry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9849950/ https://www.ncbi.nlm.nih.gov/pubmed/36683994 http://dx.doi.org/10.3389/fpsyt.2022.1065754 |
work_keys_str_mv | AT yanxiu circadianrhythmdisruptionsapossiblelinkofbipolardisorderandendocrinecomorbidities AT xupeiwei circadianrhythmdisruptionsapossiblelinkofbipolardisorderandendocrinecomorbidities AT sunxueli circadianrhythmdisruptionsapossiblelinkofbipolardisorderandendocrinecomorbidities |