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Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity
The nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) multi-subunit complex is a highly abundant and central source of reactive oxygen species. NOX2 is a key enzyme of the innate immune system involved in antibacterial response, but excessive NOX2 activity is involved in oxidative stress...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850094/ https://www.ncbi.nlm.nih.gov/pubmed/36686674 http://dx.doi.org/10.3389/fphar.2022.1075328 |