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Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity

The nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX2) multi-subunit complex is a highly abundant and central source of reactive oxygen species. NOX2 is a key enzyme of the innate immune system involved in antibacterial response, but excessive NOX2 activity is involved in oxidative stress...

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Detalles Bibliográficos
Autores principales:	Zang, Jie, Cambet, Yves, Jaquet, Vincent, Bach, Anders
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850094/ https://www.ncbi.nlm.nih.gov/pubmed/36686674 http://dx.doi.org/10.3389/fphar.2022.1075328

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