Treatment of painful calciphylaxis with methadone in a palliative care unit: A case report

A 72-year-old female was admitted with severe calciphylaxis-associated bilateral leg pain on a background of end-stage renal failure on hemodialysis. Palliative care input was requested, and following transfer to our unit she was commenced on low-dose methadone as adjunctive analgesic therapy. A rem...

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Autores principales: King, Shannon Jade, Kondasinghe, Jayamangala Sampath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dustri-Verlag Dr. Karl Feistle 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850246/
https://www.ncbi.nlm.nih.gov/pubmed/36688187
http://dx.doi.org/10.5414/CNCS110985
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author King, Shannon Jade
Kondasinghe, Jayamangala Sampath
author_facet King, Shannon Jade
Kondasinghe, Jayamangala Sampath
author_sort King, Shannon Jade
collection PubMed
description A 72-year-old female was admitted with severe calciphylaxis-associated bilateral leg pain on a background of end-stage renal failure on hemodialysis. Palliative care input was requested, and following transfer to our unit she was commenced on low-dose methadone as adjunctive analgesic therapy. A remarkable and sustained analgesic response was observed. Calciphylaxis is associated with severe pain, and careful consideration of analgesic agents and their pharmacokinetics in patients with end-stage renal failure is required.
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spelling pubmed-98502462023-01-19 Treatment of painful calciphylaxis with methadone in a palliative care unit: A case report King, Shannon Jade Kondasinghe, Jayamangala Sampath Clin Nephrol Case Stud Case Report A 72-year-old female was admitted with severe calciphylaxis-associated bilateral leg pain on a background of end-stage renal failure on hemodialysis. Palliative care input was requested, and following transfer to our unit she was commenced on low-dose methadone as adjunctive analgesic therapy. A remarkable and sustained analgesic response was observed. Calciphylaxis is associated with severe pain, and careful consideration of analgesic agents and their pharmacokinetics in patients with end-stage renal failure is required. Dustri-Verlag Dr. Karl Feistle 2023-01-12 /pmc/articles/PMC9850246/ /pubmed/36688187 http://dx.doi.org/10.5414/CNCS110985 Text en © Dustri-Verlag Dr. K. Feistle https://creativecommons.org/licenses/by/2.5/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
King, Shannon Jade
Kondasinghe, Jayamangala Sampath
Treatment of painful calciphylaxis with methadone in a palliative care unit: A case report
title Treatment of painful calciphylaxis with methadone in a palliative care unit: A case report
title_full Treatment of painful calciphylaxis with methadone in a palliative care unit: A case report
title_fullStr Treatment of painful calciphylaxis with methadone in a palliative care unit: A case report
title_full_unstemmed Treatment of painful calciphylaxis with methadone in a palliative care unit: A case report
title_short Treatment of painful calciphylaxis with methadone in a palliative care unit: A case report
title_sort treatment of painful calciphylaxis with methadone in a palliative care unit: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850246/
https://www.ncbi.nlm.nih.gov/pubmed/36688187
http://dx.doi.org/10.5414/CNCS110985
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