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Passive, active and endogenous organ-targeted lipid and polymer nanoparticles for delivery of genetic drugs
Genetic drugs based on nucleic acid biomolecules are a rapidly emerging class of medicines that directly reprogramme the central dogma of biology to prevent and treat disease. However, multiple biological barriers normally impede the intracellular delivery of nucleic acids, necessitating the use of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850348/ https://www.ncbi.nlm.nih.gov/pubmed/36691401 http://dx.doi.org/10.1038/s41578-022-00529-7 |