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Application of AOPs to assist regulatory assessment of chemical risks – Case studies, needs and recommendations
While human regulatory risk assessment (RA) still largely relies on animal studies, new approach methodologies (NAMs) based on in vitro, in silico or non-mammalian alternative models are increasingly used to evaluate chemical hazards. Moreover, human epidemiological studies with biomarkers of effect...
Autores principales: | Bajard, Lola, Adamovsky, Ondrej, Audouze, Karine, Baken, Kirsten, Barouki, Robert, Beltman, Joost B., Beronius, Anna, Bonefeld-Jørgensen, Eva Cecilie, Cano-Sancho, German, de Baat, Milo L., Di Tillio, Filippo, Fernández, Mariana F., FitzGerald, Rex E., Gundacker, Claudia, Hernández, Antonio F., Hilscherova, Klara, Karakitsios, Spyros, Kuchovska, Eliska, Long, Manhai, Luijten, Mirjam, Majid, Sanah, Marx-Stoelting, Philip, Mustieles, Vicente, Negi, Chander K., Sarigiannis, Dimosthenis, Scholz, Stefan, Sovadinova, Iva, Stierum, Rob, Tanabe, Shihori, Tollefsen, Knut Erik, van den Brand, Annick D., Vogs, Carolina, Wielsøe, Maria, Wittwehr, Clemens, Blaha, Ludek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850416/ https://www.ncbi.nlm.nih.gov/pubmed/36309218 http://dx.doi.org/10.1016/j.envres.2022.114650 |
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