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Dlk1 maintains adult mice long-term HSCs by activating Notch signaling to restrict mitochondrial metabolism

BACKGROUND: Adult hematopoietic stem cells (HSCs) homeostasis is critically important in maintaining lifelong hematopoiesis. However, how adult HSCs orchestrate its homeostasis remains not fully understood. Imprinted gene Dlk1 has been shown to play critical role in mouse embryonic hematopoiesis and...

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Detalles Bibliográficos
Autores principales:	Huang, Deyu, Han, Yingli, Tang, Tian, Yang, Lin, Jiang, Penglei, Qian, Wenchang, Zhang, Zhaoru, Qian, Xinyue, Zeng, Xin, Qian, Pengxu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850540/ https://www.ncbi.nlm.nih.gov/pubmed/36653853 http://dx.doi.org/10.1186/s40164-022-00369-9

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