Identifying foetal forebrain interneurons as a target for monogenic autism risk factors and the polygenic 16p11.2 microdeletion

BACKGROUND: Autism spectrum condition or ‘autism’ is associated with numerous genetic risk factors including the polygenic 16p11.2 microdeletion. The balance between excitatory and inhibitory neurons in the cerebral cortex is hypothesised to be critical for the aetiology of autism making improved un...

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Detalles Bibliográficos
Autores principales: Yang, Yifei, Booker, Sam A., Clegg, James M., Quintana-Urzainqui, Idoia, Sumera, Anna, Kozic, Zrinko, Dando, Owen, Martin Lorenzo, Sandra, Herault, Yann, Kind, Peter C., Price, David J., Pratt, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850541/
https://www.ncbi.nlm.nih.gov/pubmed/36658491
http://dx.doi.org/10.1186/s12868-022-00771-3

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