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Loss of TET2 impairs endothelial angiogenesis via downregulating STAT3 target genes

BACKGROUND: Ischemic diseases represent a major global health care burden. Angiogenesis is critical in recovery of blood flow and repair of injured tissue in ischemic diseases. Ten–eleven translocation protein 2 (TET2), a member of DNA demethylases, is involved in many pathological processes. Howeve...

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Detalles Bibliográficos
Autores principales: Shi, Yefei, Li, Bo, Huang, Xinru, Kou, Wenxin, Zhai, Ming, Zeng, Yanxi, You, Shuangjie, Yu, Qing, Zhao, Yifan, Zhuang, Jianhui, Peng, Wenhui, Jian, Weixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850815/
https://www.ncbi.nlm.nih.gov/pubmed/36658614
http://dx.doi.org/10.1186/s13578-023-00960-5