Cargando…

Structural Elucidation and Engineering of a Bacterial Carbohydrate Oxidase

[Image: see text] Flavin-dependent carbohydrate oxidases are valuable tools in biotechnological applications due to their high selectivity in the oxidation of carbohydrates. In this study, we report the biochemical and structural characterization of a recently discovered carbohydrate oxidase from th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Boverio, Alessandro, Widodo, Wahyu S., Santema, Lars L., Rozeboom, Henriëtte J., Xiang, Ruite, Guallar, Víctor, Mattevi, Andrea, Fraaije, Marco W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850908/ https://www.ncbi.nlm.nih.gov/pubmed/35881507 http://dx.doi.org/10.1021/acs.biochem.2c00307

Ejemplares similares

Discovery of Two Novel Oxidases Using a High‐Throughput Activity Screen
por: Rembeza, Elzbieta, et al.
Publicado: (2021)

Characterization of Two VAO-Type Flavoprotein Oxidases from Myceliophthora thermophila
por: Ferrari, Alessandro R., et al.
Publicado: (2018)

A biosynthetic aspartate N-hydroxylase performs successive oxidations by holding intermediates at a site away from the catalytic center
por: Rotilio, Laura, et al.
Publicado: (2023)

Structure-Based Engineering of Phanerochaete chrysosporium Alcohol Oxidase for Enhanced Oxidative Power toward Glycerol
por: Nguyen, Quoc-Thai, et al.
Publicado: (2018)

Structure- and computational-aided engineering of an oxidase to produce isoeugenol from a lignin-derived compound
por: Guo, Yiming, et al.
Publicado: (2022)

Characterization of two bacterial multi-flavinylated proteins harboring multiple covalent flavin cofactors
por: Tong, Yapei, et al.
Publicado: (2023)

Characterization of a New DyP-Peroxidase from the Alkaliphilic Cellulomonad, Cellulomonas bogoriensis
por: Habib, Mohamed H., et al.
Publicado: (2019)

Discovery, Biocatalytic Exploration and Structural Analysis of a 4‐Ethylphenol Oxidase from Gulosibacter chungangensis
por: Alvigini, Laura, et al.
Publicado: (2021)

EP-Pred: A Machine Learning Tool for Bioprospecting Promiscuous Ester Hydrolases
por: Xiang, Ruite, et al.
Publicado: (2022)

Biocatalytic Properties and Structural Analysis of Eugenol Oxidase from Rhodococcus jostii RHA1: A Versatile Oxidative Biocatalyst
por: Nguyen, Quoc‐Thai, et al.
Publicado: (2016)

Design of Artificial Alcohol Oxidases: Alcohol Dehydrogenase–NADPH Oxidase Fusions for Continuous Oxidations
por: Aalbers, Friso S., et al.
Publicado: (2018)

Rational Engineering of a Flavoprotein Oxidase for Improved Direct Oxidation of Alcohols to Carboxylic Acids
por: Pickl, Mathias, et al.
Publicado: (2017)

Mutational and structural analysis of an ancestral fungal dye‐decolorizing peroxidase
por: Zitare, Ulises A., et al.
Publicado: (2021)

Active-Site Engineering Switches Carbohydrate Regiospecificity in a Fungal Copper Radical Oxidase
por: Mathieu, Yann, et al.
Publicado: (2022)

Production of Hydroxy Acids: Selective Double Oxidation of Diols by Flavoprotein Alcohol Oxidase
por: Martin, Caterina, et al.
Publicado: (2020)

Approaching boiling point stability of an alcohol dehydrogenase through computationally-guided enzyme engineering
por: Aalbers, Friso S, et al.
Publicado: (2020)

Creating Oxidase–Peroxidase Fusion Enzymes as a Toolbox for Cascade Reactions
por: Colpa, Dana I., et al.
Publicado: (2017)

Characterization and Crystal Structure of a Robust Cyclohexanone Monooxygenase
por: Romero, Elvira, et al.
Publicado: (2016)

Molecular Basis for Converting (2S)-Methylsuccinyl-CoA Dehydrogenase into an Oxidase
por: Burgener, Simon, et al.
Publicado: (2017)

Discovery and characterization of an F(420)-dependent glucose-6-phosphate dehydrogenase (Rh-FGD1) from Rhodococcus jostii RHA1
por: Nguyen, Quoc-Thai, et al.
Publicado: (2016)

The Biocatalytic Synthesis of Syringaresinol from 2,6-Dimethoxy-4-allylphenol in One-Pot Using a Tailored Oxidase/Peroxidase System
por: Habib, Mohamed, et al.
Publicado: (2018)

Ancestral reconstruction of mammalian FMO1 enables structural determination, revealing unique features that explain its catalytic properties
por: Bailleul, Gautier, et al.
Publicado: (2020)

Elucidating Carbohydrate-Protein Interactions Using Nanoparticle-Based Approaches
por: Kim, Dongyoon, et al.
Publicado: (2021)

Insights into peculiar fungal LPMO family members holding a short C-terminal sequence reminiscent of phosphate binding motifs
por: Reyre, Jean-Lou, et al.
Publicado: (2023)

On the mechanism of calcium‐dependent activation of NADPH oxidase 5 (NOX5)
por: Millana Fañanás, Elisa, et al.
Publicado: (2019)

Architecture of the NADPH oxidase family of enzymes
por: Ogboo, Blessing C., et al.
Publicado: (2022)

The ins and outs of vanillyl alcohol oxidase: Identification of ligand migration paths
por: Gygli, Gudrun, et al.
Publicado: (2017)

Creating a more robust 5-hydroxymethylfurfural oxidase by combining computational predictions with a novel effective library design
por: Martin, Caterina, et al.
Publicado: (2018)

Evolution of enzyme functionality in the flavin-containing monooxygenases
por: Bailleul, Gautier, et al.
Publicado: (2023)

Export of functional Streptomyces coelicolor alditol oxidase to the periplasm or cell surface of Escherichia coli and its application in whole-cell biocatalysis
por: van Bloois, Edwin, et al.
Publicado: (2009)

Concomitant Prevalence of Low Serum Diamine Oxidase Activity and Carbohydrate Malabsorption
por: Enko, Dietmar, et al.
Publicado: (2016)

Discovery and characterization of a putrescine oxidase from Rhodococcus erythropolis NCIMB 11540
por: van Hellemond, Erik W., et al.
Publicado: (2008)

Side-Chain Pruning Has Limited Impact on Substrate Preference in a Promiscuous Enzyme
por: Fürst, Maximilian J. L. J., et al.
Publicado: (2018)

Multiple implications of an active site phenylalanine in the catalysis of aryl-alcohol oxidase
por: Carro, Juan, et al.
Publicado: (2018)

Biocatalytic Enantioselective Oxidation of Sec‐Allylic Alcohols with Flavin‐Dependent Oxidases
por: Gandomkar, Somayyeh, et al.
Publicado: (2019)

Elucidation of a Unique Pattern and the Role of Carbohydrate Binding Module of an Alginate Lyase
por: Hu, Fu, et al.
Publicado: (2019)

Elucidating Sequence and Structural Determinants of Carbohydrate Esterases for Complete Deacetylation of Substituted Xylans
por: Penttinen, Leena, et al.
Publicado: (2022)

Evolutionary and structural analyses of the NADPH oxidase family in eukaryotes reveal an initial calcium dependency
por: Massari, Marta, et al.
Publicado: (2022)

Monoamine Oxidases, Oxidative Stress, and Altered Mitochondrial Dynamics in Cardiac Ageing
por: Maggiorani, Damien, et al.
Publicado: (2017)

Vanillyl alcohol oxidase from Diplodia corticola: Residues Ala420 and Glu466 allow for efficient catalysis of syringyl derivatives
por: Eggerichs, Daniel, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_dr9sd0hrutbqa062lv0dv9ttpa