Identification of Kazal Inhibitor Scaffolds with Identical Canonical Binding Loops and Their Effects on Binding Properties

[Image: see text] Kazal inhibitors hold high potential as scaffolds for therapeutic molecules, taking advantage of the easily exchangeable canonical binding loop. Different Kazal inhibitor backbones have been suggested to be therapeutically useful, but the impact of different Kazal-like scaffolds on...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagel, Felix, Susemihl, Anne, Eulberg, Tobias, Delcea, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850914/
https://www.ncbi.nlm.nih.gov/pubmed/36598875
http://dx.doi.org/10.1021/acs.biochem.2c00573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850914/
https://www.ncbi.nlm.nih.gov/pubmed/36598875
http://dx.doi.org/10.1021/acs.biochem.2c00573

Ejemplares similares