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Biophysical Characterization of the Contribution of the Fab Region to the IgG-FcγRIIIa Interaction

[Image: see text] The cell-surface receptor FcγRIIIa is crucial to the efficacy of therapeutic antibodies as well as the immune response. The interaction of the Fc region of IgG molecules with FcγRIIIa has been characterized, but until recently, it was thought that the Fab regions were not involved...

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Detalles Bibliográficos
Autores principales:	Kosuge, Hirofumi, Nagatoishi, Satoru, Kiyoshi, Masato, Ishii-Watabe, Akiko, Terao, Yosuke, Ide, Teruhiko, Tsumoto, Kouhei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850916/ https://www.ncbi.nlm.nih.gov/pubmed/35605982 http://dx.doi.org/10.1021/acs.biochem.1c00832

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