Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries

The review focuses on the most important areas of cell therapy for spinal cord injuries. Olfactory mucosa cells are promising for transplantation. Obtaining these cells is safe for patients. The use of olfactory mucosa cells is effective in restoring motor function due to the remyelination and regen...

Descripción completa

Detalles Bibliográficos
Autores principales: Stepanova, Olga Vladislavovna, Fursa, Grigorii Andreevich, Andretsova, Svetlana Sergeevna, Shishkina, Valentina Sergeevna, Voronova, Anastasia Denisovna, Chadin, Andrey Viktorovich, Karsuntseva, Ekaterina Konstantinovna, Reshetov, Igor Vladimirovich, Chekhonin, Vladimir Pavlovich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850961/
https://www.ncbi.nlm.nih.gov/pubmed/36686356
http://dx.doi.org/10.12998/wjcc.v11.i2.322
_version_ 1784872301772144640
author Stepanova, Olga Vladislavovna
Fursa, Grigorii Andreevich
Andretsova, Svetlana Sergeevna
Shishkina, Valentina Sergeevna
Voronova, Anastasia Denisovna
Chadin, Andrey Viktorovich
Karsuntseva, Ekaterina Konstantinovna
Reshetov, Igor Vladimirovich
Chekhonin, Vladimir Pavlovich
author_facet Stepanova, Olga Vladislavovna
Fursa, Grigorii Andreevich
Andretsova, Svetlana Sergeevna
Shishkina, Valentina Sergeevna
Voronova, Anastasia Denisovna
Chadin, Andrey Viktorovich
Karsuntseva, Ekaterina Konstantinovna
Reshetov, Igor Vladimirovich
Chekhonin, Vladimir Pavlovich
author_sort Stepanova, Olga Vladislavovna
collection PubMed
description The review focuses on the most important areas of cell therapy for spinal cord injuries. Olfactory mucosa cells are promising for transplantation. Obtaining these cells is safe for patients. The use of olfactory mucosa cells is effective in restoring motor function due to the remyelination and regeneration of axons after spinal cord injuries. These cells express neurotrophic factors that play an important role in the functional recovery of nerve tissue after spinal cord injuries. In addition, it is possible to increase the content of neurotrophic factors, at the site of injury, exogenously by the direct injection of neurotrophic factors or their delivery using gene therapy. The advantages of olfactory mucosa cells, in combination with neurotrophic factors, open up wide possibilities for their application in three-dimensional and four-dimensional bioprinting technology treating spinal cord injuries.
format Online
Article
Text
id pubmed-9850961
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Baishideng Publishing Group Inc
record_format MEDLINE/PubMed
spelling pubmed-98509612023-01-20 Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries Stepanova, Olga Vladislavovna Fursa, Grigorii Andreevich Andretsova, Svetlana Sergeevna Shishkina, Valentina Sergeevna Voronova, Anastasia Denisovna Chadin, Andrey Viktorovich Karsuntseva, Ekaterina Konstantinovna Reshetov, Igor Vladimirovich Chekhonin, Vladimir Pavlovich World J Clin Cases Minireviews The review focuses on the most important areas of cell therapy for spinal cord injuries. Olfactory mucosa cells are promising for transplantation. Obtaining these cells is safe for patients. The use of olfactory mucosa cells is effective in restoring motor function due to the remyelination and regeneration of axons after spinal cord injuries. These cells express neurotrophic factors that play an important role in the functional recovery of nerve tissue after spinal cord injuries. In addition, it is possible to increase the content of neurotrophic factors, at the site of injury, exogenously by the direct injection of neurotrophic factors or their delivery using gene therapy. The advantages of olfactory mucosa cells, in combination with neurotrophic factors, open up wide possibilities for their application in three-dimensional and four-dimensional bioprinting technology treating spinal cord injuries. Baishideng Publishing Group Inc 2023-01-16 2023-01-16 /pmc/articles/PMC9850961/ /pubmed/36686356 http://dx.doi.org/10.12998/wjcc.v11.i2.322 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Minireviews
Stepanova, Olga Vladislavovna
Fursa, Grigorii Andreevich
Andretsova, Svetlana Sergeevna
Shishkina, Valentina Sergeevna
Voronova, Anastasia Denisovna
Chadin, Andrey Viktorovich
Karsuntseva, Ekaterina Konstantinovna
Reshetov, Igor Vladimirovich
Chekhonin, Vladimir Pavlovich
Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries
title Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries
title_full Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries
title_fullStr Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries
title_full_unstemmed Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries
title_short Prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries
title_sort prospects for the use of olfactory mucosa cells in bioprinting for the treatment of spinal cord injuries
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850961/
https://www.ncbi.nlm.nih.gov/pubmed/36686356
http://dx.doi.org/10.12998/wjcc.v11.i2.322
work_keys_str_mv AT stepanovaolgavladislavovna prospectsfortheuseofolfactorymucosacellsinbioprintingforthetreatmentofspinalcordinjuries
AT fursagrigoriiandreevich prospectsfortheuseofolfactorymucosacellsinbioprintingforthetreatmentofspinalcordinjuries
AT andretsovasvetlanasergeevna prospectsfortheuseofolfactorymucosacellsinbioprintingforthetreatmentofspinalcordinjuries
AT shishkinavalentinasergeevna prospectsfortheuseofolfactorymucosacellsinbioprintingforthetreatmentofspinalcordinjuries
AT voronovaanastasiadenisovna prospectsfortheuseofolfactorymucosacellsinbioprintingforthetreatmentofspinalcordinjuries
AT chadinandreyviktorovich prospectsfortheuseofolfactorymucosacellsinbioprintingforthetreatmentofspinalcordinjuries
AT karsuntsevaekaterinakonstantinovna prospectsfortheuseofolfactorymucosacellsinbioprintingforthetreatmentofspinalcordinjuries
AT reshetovigorvladimirovich prospectsfortheuseofolfactorymucosacellsinbioprintingforthetreatmentofspinalcordinjuries
AT chekhoninvladimirpavlovich prospectsfortheuseofolfactorymucosacellsinbioprintingforthetreatmentofspinalcordinjuries

Ejemplares similares