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Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report

BACKGROUND: Coronavirus disease 2019 (COVID-19) has spread rapidly, resulting in a pandemic in January 2020. Few studies have focused on the natural history and consequences of acute liver injury (ALI) in mild or asymptomatic COVID-19 patients, manifested by elevated aminotransferase levels. ALI is...

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Autores principales: Lai, Pei-Hsuan, Ding, Dah-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850972/
https://www.ncbi.nlm.nih.gov/pubmed/36686361
http://dx.doi.org/10.12998/wjcc.v11.i2.472
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author Lai, Pei-Hsuan
Ding, Dah-Ching
author_facet Lai, Pei-Hsuan
Ding, Dah-Ching
author_sort Lai, Pei-Hsuan
collection PubMed
description BACKGROUND: Coronavirus disease 2019 (COVID-19) has spread rapidly, resulting in a pandemic in January 2020. Few studies have focused on the natural history and consequences of acute liver injury (ALI) in mild or asymptomatic COVID-19 patients, manifested by elevated aminotransferase levels. ALI is usually expected for severe COVID-19 cases. Here, we present a COVID-19 case with mild respiratory symptoms and significantly elevated alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. CASE SUMMARY: A 60-year-old woman without medical history or chronic illness received three COVID-19 vaccinations since the start of the pandemic. The patient was infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and presented with mild symptoms on July 12(th), 2022. Post-recovery, she underwent an examination at our hospital on August 30(th), 2022. AST and ALT levels in the liver function test were 207 U/L (normal value < 39, 5.3-fold increase) and 570 U/L (normal value < 52, 10.9-fold increase), respectively. The patient was diagnosed with ALI, and no treatment was prescribed. The following week, blood tests showed a reduction in both levels (ALT 124 U/L, AST 318 U/L). Two weeks later, AST and ALT levels had decreased to near the expected upper limits (ALT 40 U/L, AST 76 U/L). CONCLUSION: Clinicians should pay attention to liver function testing during COVID-19 recovery regardless of the disease’s severity.
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spelling pubmed-98509722023-01-20 Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report Lai, Pei-Hsuan Ding, Dah-Ching World J Clin Cases Case Report BACKGROUND: Coronavirus disease 2019 (COVID-19) has spread rapidly, resulting in a pandemic in January 2020. Few studies have focused on the natural history and consequences of acute liver injury (ALI) in mild or asymptomatic COVID-19 patients, manifested by elevated aminotransferase levels. ALI is usually expected for severe COVID-19 cases. Here, we present a COVID-19 case with mild respiratory symptoms and significantly elevated alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. CASE SUMMARY: A 60-year-old woman without medical history or chronic illness received three COVID-19 vaccinations since the start of the pandemic. The patient was infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and presented with mild symptoms on July 12(th), 2022. Post-recovery, she underwent an examination at our hospital on August 30(th), 2022. AST and ALT levels in the liver function test were 207 U/L (normal value < 39, 5.3-fold increase) and 570 U/L (normal value < 52, 10.9-fold increase), respectively. The patient was diagnosed with ALI, and no treatment was prescribed. The following week, blood tests showed a reduction in both levels (ALT 124 U/L, AST 318 U/L). Two weeks later, AST and ALT levels had decreased to near the expected upper limits (ALT 40 U/L, AST 76 U/L). CONCLUSION: Clinicians should pay attention to liver function testing during COVID-19 recovery regardless of the disease’s severity. Baishideng Publishing Group Inc 2023-01-16 2023-01-16 /pmc/articles/PMC9850972/ /pubmed/36686361 http://dx.doi.org/10.12998/wjcc.v11.i2.472 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Case Report
Lai, Pei-Hsuan
Ding, Dah-Ching
Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report
title Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report
title_full Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report
title_fullStr Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report
title_full_unstemmed Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report
title_short Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report
title_sort acute liver injury in a covid-19 infected woman with mild symptoms: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850972/
https://www.ncbi.nlm.nih.gov/pubmed/36686361
http://dx.doi.org/10.12998/wjcc.v11.i2.472
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