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Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report
BACKGROUND: Coronavirus disease 2019 (COVID-19) has spread rapidly, resulting in a pandemic in January 2020. Few studies have focused on the natural history and consequences of acute liver injury (ALI) in mild or asymptomatic COVID-19 patients, manifested by elevated aminotransferase levels. ALI is...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850972/ https://www.ncbi.nlm.nih.gov/pubmed/36686361 http://dx.doi.org/10.12998/wjcc.v11.i2.472 |
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author | Lai, Pei-Hsuan Ding, Dah-Ching |
author_facet | Lai, Pei-Hsuan Ding, Dah-Ching |
author_sort | Lai, Pei-Hsuan |
collection | PubMed |
description | BACKGROUND: Coronavirus disease 2019 (COVID-19) has spread rapidly, resulting in a pandemic in January 2020. Few studies have focused on the natural history and consequences of acute liver injury (ALI) in mild or asymptomatic COVID-19 patients, manifested by elevated aminotransferase levels. ALI is usually expected for severe COVID-19 cases. Here, we present a COVID-19 case with mild respiratory symptoms and significantly elevated alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. CASE SUMMARY: A 60-year-old woman without medical history or chronic illness received three COVID-19 vaccinations since the start of the pandemic. The patient was infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and presented with mild symptoms on July 12(th), 2022. Post-recovery, she underwent an examination at our hospital on August 30(th), 2022. AST and ALT levels in the liver function test were 207 U/L (normal value < 39, 5.3-fold increase) and 570 U/L (normal value < 52, 10.9-fold increase), respectively. The patient was diagnosed with ALI, and no treatment was prescribed. The following week, blood tests showed a reduction in both levels (ALT 124 U/L, AST 318 U/L). Two weeks later, AST and ALT levels had decreased to near the expected upper limits (ALT 40 U/L, AST 76 U/L). CONCLUSION: Clinicians should pay attention to liver function testing during COVID-19 recovery regardless of the disease’s severity. |
format | Online Article Text |
id | pubmed-9850972 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Baishideng Publishing Group Inc |
record_format | MEDLINE/PubMed |
spelling | pubmed-98509722023-01-20 Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report Lai, Pei-Hsuan Ding, Dah-Ching World J Clin Cases Case Report BACKGROUND: Coronavirus disease 2019 (COVID-19) has spread rapidly, resulting in a pandemic in January 2020. Few studies have focused on the natural history and consequences of acute liver injury (ALI) in mild or asymptomatic COVID-19 patients, manifested by elevated aminotransferase levels. ALI is usually expected for severe COVID-19 cases. Here, we present a COVID-19 case with mild respiratory symptoms and significantly elevated alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. CASE SUMMARY: A 60-year-old woman without medical history or chronic illness received three COVID-19 vaccinations since the start of the pandemic. The patient was infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and presented with mild symptoms on July 12(th), 2022. Post-recovery, she underwent an examination at our hospital on August 30(th), 2022. AST and ALT levels in the liver function test were 207 U/L (normal value < 39, 5.3-fold increase) and 570 U/L (normal value < 52, 10.9-fold increase), respectively. The patient was diagnosed with ALI, and no treatment was prescribed. The following week, blood tests showed a reduction in both levels (ALT 124 U/L, AST 318 U/L). Two weeks later, AST and ALT levels had decreased to near the expected upper limits (ALT 40 U/L, AST 76 U/L). CONCLUSION: Clinicians should pay attention to liver function testing during COVID-19 recovery regardless of the disease’s severity. Baishideng Publishing Group Inc 2023-01-16 2023-01-16 /pmc/articles/PMC9850972/ /pubmed/36686361 http://dx.doi.org/10.12998/wjcc.v11.i2.472 Text en ©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
spellingShingle | Case Report Lai, Pei-Hsuan Ding, Dah-Ching Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report |
title | Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report |
title_full | Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report |
title_fullStr | Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report |
title_full_unstemmed | Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report |
title_short | Acute liver injury in a COVID-19 infected woman with mild symptoms: A case report |
title_sort | acute liver injury in a covid-19 infected woman with mild symptoms: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9850972/ https://www.ncbi.nlm.nih.gov/pubmed/36686361 http://dx.doi.org/10.12998/wjcc.v11.i2.472 |
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