In vivo dynamics and anti-tumor effects of EpCAM-directed CAR T-cells against brain metastases from lung cancer

Lung cancer patients are at risk for brain metastases and often succumb to their intracranial disease. Chimeric Antigen Receptor (CAR) T-cells emerged as a powerful cell-based immunotherapy for hematological malignancies; however, it remains unclear whether CAR T-cells represent a viable therapy for...

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Detalles Bibliográficos
Autores principales: Xu, Tao, Karschnia, Philipp, Cadilha, Bruno Loureiro, Dede, Sertac, Lorenz, Michael, Seewaldt, Niklas, Nikolaishvili, Elene, Müller, Katharina, Blobner, Jens, Teske, Nico, Herold, Julika J., Rejeski, Kai, Langer, Sigrid, Obeck, Hannah, Lorenzini, Theo, Mulazzani, Matthias, Zhang, Wenlong, Ishikawa-Ankerhold, Hellen, Buchholz, Veit R., Subklewe, Marion, Thon, Niklas, Straube, Andreas, Tonn, Joerg-Christian, Kobold, Sebastian, von Baumgarten, Louisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851202/
https://www.ncbi.nlm.nih.gov/pubmed/36687005
http://dx.doi.org/10.1080/2162402X.2022.2163781

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