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Systematic benchmarking of statistical methods to assess differential expression of circular RNAs
Circular RNAs (circRNAs) are covalently closed transcripts involved in critical regulatory axes, cancer pathways and disease mechanisms. CircRNA expression measured with RNA-seq has particular characteristics that might hamper the performance of standard biostatistical differential expression assess...
Autores principales: | Buratin, Alessia, Bortoluzzi, Stefania, Gaffo, Enrico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851295/ https://www.ncbi.nlm.nih.gov/pubmed/36592056 http://dx.doi.org/10.1093/bib/bbac612 |
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