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RNAdegformer: accurate prediction of mRNA degradation at nucleotide resolution with deep learning

Messenger RNA-based therapeutics have shown tremendous potential, as demonstrated by the rapid development of messenger RNA based vaccines for COVID-19. Nevertheless, distribution of mRNA vaccines worldwide has been hampered by mRNA’s inherent thermal instability due to in-line hydrolysis, a chemica...

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Detalles Bibliográficos
Autores principales:	He, Shujun, Gao, Baizhen, Sabnis, Rushant, Sun, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Problem Solving Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851316/ https://www.ncbi.nlm.nih.gov/pubmed/36633966 http://dx.doi.org/10.1093/bib/bbac581

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