Cargando…
Are olfactory and gustatory symptoms useful at predicting disease severity markers in COVID-19 infection?
CONTEXT: The relationship between olfactory and gustatory dysfunction (OGD) and COVID-19 infection severity is still unclear. AIM: To investigate the correlation between OGD in COVID-19-infected individuals and RT-PCR results, chest CT scan abnormality, lymphocyte counts, hospital admission units, a...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851345/ https://www.ncbi.nlm.nih.gov/pubmed/36683935 http://dx.doi.org/10.4103/njms.njms_38_22 |
_version_ | 1784872375755472896 |
---|---|
author | Falaki, Mojgan Abdi, Saeed Shafiei, Shervin Moslemi, Mohammadreza Nobar, Behrad Rahbani Tabrizi, Reza Mohammadikhah, Meysam Moslemi, Hamidreza |
author_facet | Falaki, Mojgan Abdi, Saeed Shafiei, Shervin Moslemi, Mohammadreza Nobar, Behrad Rahbani Tabrizi, Reza Mohammadikhah, Meysam Moslemi, Hamidreza |
author_sort | Falaki, Mojgan |
collection | PubMed |
description | CONTEXT: The relationship between olfactory and gustatory dysfunction (OGD) and COVID-19 infection severity is still unclear. AIM: To investigate the correlation between OGD in COVID-19-infected individuals and RT-PCR results, chest CT scan abnormality, lymphocyte counts, hospital admission units, age, body temperature, and blood oxygen saturation. SETTING AND DESIGN: Case–control study. MATERIALS AND METHODS: The sample was composed of laboratory and chest X-ray confirmed COVID-19-infected patients from four hospitals. The patients were divided into case and control groups based on the presence of OGD symptoms. The predictor variable was OGD. The outcome variable was gender, hospital admission unit, chest CT scan abnormality, PCR, lymphocyte counts, age, body temperature, and blood oxygen saturation. STATISTICAL ANALYSIS USED: Bivariate statistics were computed and the P value was set at 0.05. RESULTS: The sample consisted of 189 patients. Smell and taste disorders were found in 31.7% and 24.3% of patients, respectively. OGD was significantly correlated with positive PCR results (P < 0.001) and general unit admission (P < 0.05) during hospitalization. Additionally, patients with OGD had significantly lower mean age (P < 0.001), higher body temperature (P < 0.01), and blood oxygen saturation (P < 0.01). However, OGD was not correlated with gender, chest CT scan abnormality, or lymphocyte counts (P > 0.05). CONCLUSIONS: OGD symptoms can be used to detect COVID-19-infected patients. OGD can be used to predict less severe disease mainly by its correlation with the less amount of hospital care, more negative PCR results, higher body temperature, and higher blood oxygen saturation. |
format | Online Article Text |
id | pubmed-9851345 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-98513452023-01-20 Are olfactory and gustatory symptoms useful at predicting disease severity markers in COVID-19 infection? Falaki, Mojgan Abdi, Saeed Shafiei, Shervin Moslemi, Mohammadreza Nobar, Behrad Rahbani Tabrizi, Reza Mohammadikhah, Meysam Moslemi, Hamidreza Natl J Maxillofac Surg Original Article CONTEXT: The relationship between olfactory and gustatory dysfunction (OGD) and COVID-19 infection severity is still unclear. AIM: To investigate the correlation between OGD in COVID-19-infected individuals and RT-PCR results, chest CT scan abnormality, lymphocyte counts, hospital admission units, age, body temperature, and blood oxygen saturation. SETTING AND DESIGN: Case–control study. MATERIALS AND METHODS: The sample was composed of laboratory and chest X-ray confirmed COVID-19-infected patients from four hospitals. The patients were divided into case and control groups based on the presence of OGD symptoms. The predictor variable was OGD. The outcome variable was gender, hospital admission unit, chest CT scan abnormality, PCR, lymphocyte counts, age, body temperature, and blood oxygen saturation. STATISTICAL ANALYSIS USED: Bivariate statistics were computed and the P value was set at 0.05. RESULTS: The sample consisted of 189 patients. Smell and taste disorders were found in 31.7% and 24.3% of patients, respectively. OGD was significantly correlated with positive PCR results (P < 0.001) and general unit admission (P < 0.05) during hospitalization. Additionally, patients with OGD had significantly lower mean age (P < 0.001), higher body temperature (P < 0.01), and blood oxygen saturation (P < 0.01). However, OGD was not correlated with gender, chest CT scan abnormality, or lymphocyte counts (P > 0.05). CONCLUSIONS: OGD symptoms can be used to detect COVID-19-infected patients. OGD can be used to predict less severe disease mainly by its correlation with the less amount of hospital care, more negative PCR results, higher body temperature, and higher blood oxygen saturation. Wolters Kluwer - Medknow 2022 2022-12-10 /pmc/articles/PMC9851345/ /pubmed/36683935 http://dx.doi.org/10.4103/njms.njms_38_22 Text en Copyright: © 2022 National Journal of Maxillofacial Surgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Falaki, Mojgan Abdi, Saeed Shafiei, Shervin Moslemi, Mohammadreza Nobar, Behrad Rahbani Tabrizi, Reza Mohammadikhah, Meysam Moslemi, Hamidreza Are olfactory and gustatory symptoms useful at predicting disease severity markers in COVID-19 infection? |
title | Are olfactory and gustatory symptoms useful at predicting disease severity markers in COVID-19 infection? |
title_full | Are olfactory and gustatory symptoms useful at predicting disease severity markers in COVID-19 infection? |
title_fullStr | Are olfactory and gustatory symptoms useful at predicting disease severity markers in COVID-19 infection? |
title_full_unstemmed | Are olfactory and gustatory symptoms useful at predicting disease severity markers in COVID-19 infection? |
title_short | Are olfactory and gustatory symptoms useful at predicting disease severity markers in COVID-19 infection? |
title_sort | are olfactory and gustatory symptoms useful at predicting disease severity markers in covid-19 infection? |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851345/ https://www.ncbi.nlm.nih.gov/pubmed/36683935 http://dx.doi.org/10.4103/njms.njms_38_22 |
work_keys_str_mv | AT falakimojgan areolfactoryandgustatorysymptomsusefulatpredictingdiseaseseveritymarkersincovid19infection AT abdisaeed areolfactoryandgustatorysymptomsusefulatpredictingdiseaseseveritymarkersincovid19infection AT shafieishervin areolfactoryandgustatorysymptomsusefulatpredictingdiseaseseveritymarkersincovid19infection AT moslemimohammadreza areolfactoryandgustatorysymptomsusefulatpredictingdiseaseseveritymarkersincovid19infection AT nobarbehradrahbani areolfactoryandgustatorysymptomsusefulatpredictingdiseaseseveritymarkersincovid19infection AT tabrizireza areolfactoryandgustatorysymptomsusefulatpredictingdiseaseseveritymarkersincovid19infection AT mohammadikhahmeysam areolfactoryandgustatorysymptomsusefulatpredictingdiseaseseveritymarkersincovid19infection AT moslemihamidreza areolfactoryandgustatorysymptomsusefulatpredictingdiseaseseveritymarkersincovid19infection |